Head-to-head · Cost-Efficiency Index
OnlyRx vs Rehydra+ Wellness
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
OnlyRx
Shoppers who want a 50-state marketplace with multiple pharmacy options and named prescribers.
Visit OnlyRxRehydra+ Wellness
Shoppers who want to buy a single four-week supply without a subscription, in one of the states it serves.
Visit Rehydra+ WellnessThe verdict
OnlyRx and Rehydra+ Wellness tie on the Cost-Efficiency Index at 64/100, so neither wins outright on the numbers, so choose on fit. OnlyRx: Shoppers who want a 50-state marketplace with multiple pharmacy options and named prescribers. Rehydra+ Wellness: Shoppers who want to buy a single four-week supply without a subscription, in one of the states it serves.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs OnlyRx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | OnlyRx | Rehydra+ Wellness |
|---|---|---|
| Cost-Efficiency Index | 64/100 | 64/100 |
| Semaglutide / mo | $179/moStarting dose, compounded | $149For a 4-week supply (0.25 mg, one-time purchase, compounded; $179–$289 at higher doses) |
| Tirzepatide / mo | $249/moStarting dose, compounded | $219For a 4-week supply (2.5 mg, one-time purchase, compounded; $249–$649 at higher doses) |
| Semaglutide / yr (modeled) | $2,148 | $1,93713 charges |
| Tirzepatide / yr (modeled) | $2,988 | $2,84713 charges |
| Coverage | Coverage not published | 20 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #222 | #229 |
OnlyRx
64/100Where the value is
- Serves all 50 states per its own claim, wider than most compounded-GLP-1 competitors
- Two named prescribers with published NPI numbers (Dr. Ana Lisa Carr, Dr. Kelly Tenbrink), plus two supporting providers
- Sources medication from four named, recognizable 503A-style pharmacy partners rather than one undisclosed source
The tradeoffs
- The $179 headline price is explicitly labeled a 'Summer Promo' on the site's own homepage — no post-promo price is published
- No dose-tier (mg) breakdown is published for any of the four price points
Rehydra+ Wellness
64/100Where the value is
- Four-week supply packs are one-time purchases, so you can buy a month of treatment without a subscription
- Prices for every dose and for four-, eight- and twelve-week supplies are shown on the product pages before you start
- The membership page prints the six-month, non-cancelable term right beside each membership price
The tradeoffs
- Every semaglutide and tirzepatide membership, from $119 and $169 a month, is a six-month contract the site calls non-cancelable
- Supply-pack prices climb steeply with dose: tirzepatide reaches $649 for four weeks at 15 mg
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.