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WeighLab

One80Rx vs altRX

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

One80Rx

Provider comparison

Shoppers who want an injectable or oral GLP-1 with peptide therapies on the same account and will confirm their exact price after the provider review.

Semaglutide / month
$129/moStarting price, compounded; confirmed after provider review
Tirzepatide / month
$229/moStarting price, compounded; confirmed after provider review
Index 72/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check One80Rx pricing Read review

altRX

Provider comparison

Shoppers who want one compounded price that stays the same at every dose.

Semaglutide / month
$89/moAll doses, compounded
Tirzepatide / month
$149/moAll doses, compounded
Index 70/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check altRX pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

One80Rx has the higher Cost-Efficiency Index: 72/100 versus 70/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

One80Rx
Not published
altRX
Coverage not published

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

One80Rx

altRX

Semaglutide / month
One80Rx: $129/moStarting price, compounded; confirmed after provider review
altRX: $89/moAll doses, compounded
Tirzepatide / month
One80Rx: $229/moStarting price, compounded; confirmed after provider review
altRX: $149/moAll doses, compounded
Semaglutide / year (modeled)
One80Rx: $1,548
altRX: $1,068
Tirzepatide / year (modeled)
One80Rx: $2,748
altRX: $1,788
State availability
One80Rx: Not published
altRX: Coverage not published
Oral / sublingual option listed
One80Rx: Yes
altRX: Not listed
Brand-name access listed
One80Rx: Not confirmed
altRX: Yes
Provider facts checked
One80Rx: October 2026
altRX: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

One80Rx

Shoppers who want an injectable or oral GLP-1 with peptide therapies on the same account and will confirm their exact price after the provider review.

Reasons to consider it

  • Starting prices for every program are listed on its treatments page: semaglutide $129, a GLP-1 microdose $149, an oral GLP-1 $149 and tirzepatide $229 a month
  • Promises flat-rate pricing with no consultation charge and no surcharge when your dose changes
  • You pay $0 if you aren't approved, and shipping is free in two to three days

What to weigh up

  • Every price is a "from" figure, and the site says plans are confirmed after provider review, so the price for your dose isn't published
  • The semaglutide and tirzepatide program pages show no price at all; the figures appear only on the homepage banner and the treatments list
  • It doesn't name its compounding pharmacies or its medical group, and says only that it serves the states where it is licensed

Compounded drugs are not FDA-approved. Understand the medication options.

Check One80Rx pricing Read the full One80Rx review

altRX

Shoppers who want one compounded price that stays the same at every dose.

Reasons to consider it

  • Same price at every dose — titrating up does not raise the monthly cost, unlike per-mg-tiered competitors
  • No membership fee, no insurance required; price stated to be all-in (consultation, dosing plan, medication, free delivery, clinician support)
  • LegitScript certified

What to weigh up

  • The site runs countdown banners saying the price is about to rise, but $89 and $149 have stayed in place past each deadline, so don't rush a decision on account of the clock
  • No compounding pharmacy is individually named, only '503A compounding pharmacies within the altRx network'
  • No states-served list is published; the only geographic detail is special handling for California residents

Regulatory note: the FDA issued a warning letter to Trinity HealthCare Supply, LLC dba altRx in June 2026. We still list and link to altRX; you should know the letter is on the public record before you decide.

Compounded drugs are not FDA-approved. Understand the medication options.

Check altRX pricing Read the full altRX review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

One80RxaltRX
Normalized Cost/Month
One80Rx:
92/100
altRX:
88/100
Price Transparency
One80Rx:
94/100
altRX:
94/100
Nationwide Access
One80Rx:
24/100
altRX:
24/100
Formulation Options
One80Rx:
77/100
altRX:
79/100
Clinical Oversight
One80Rx:
73/100
altRX:
70/100
Contract Flexibility
One80Rx:
61/100
altRX:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.