Oak vs PlexusDx

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Oak

Affiliate partner

Shoppers who want one price at every dose, no subscription, and the option of a brand-name pen or the Wegovy pill on the same account.

Semaglutide / month: $250/moSame price at every dose; $200/mo on a 3-month supply paid upfront
Tirzepatide / month: $300/moSame price at every dose; $267/mo on a 3-month supply paid upfront

Index 77/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Oak pricing Read review

PlexusDx

Provider comparison

Shoppers who want one price at every dose, an oral option for either molecule, and all 50 states.

Semaglutide / month: $189/moSame price at every dose, month to month, compounded, all-inclusive; $169/mo on a 3-month plan, $149/mo on a 6-month plan
Tirzepatide / month: $289/moSame price at every dose, month to month, compounded, all-inclusive; $269/mo on a 3-month plan, $249/mo on a 6-month plan

Index 79/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check PlexusDx pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

PlexusDx has the higher Cost-Efficiency Index: 79/100 versus 77/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Oak: 45 states (list not published)
PlexusDx: All 50 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Oak

PlexusDx

Semaglutide / month: Oak: $250/moSame price at every dose; $200/mo on a 3-month supply paid upfront; PlexusDx: $189/moSame price at every dose, month to month, compounded, all-inclusive; $169/mo on a 3-month plan, $149/mo on a 6-month plan

Tirzepatide / month: Oak: $300/moSame price at every dose; $267/mo on a 3-month supply paid upfront; PlexusDx: $289/moSame price at every dose, month to month, compounded, all-inclusive; $269/mo on a 3-month plan, $249/mo on a 6-month plan

Semaglutide / year (modeled): Oak: $3,000; PlexusDx: $2,268

Tirzepatide / year (modeled): Oak: $3,600; PlexusDx: $3,468

State availability: Oak: 45 states (list not published); PlexusDx: All 50 states

Oral / sublingual option listed: Oak: Yes; PlexusDx: Yes

Brand-name access listed: Oak: Yes; PlexusDx: Not confirmed

Provider facts checked: Oak: October 2026; PlexusDx: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Oak

Shoppers who want one price at every dose, no subscription, and the option of a brand-name pen or the Wegovy pill on the same account.

Reasons to consider it

One price at every dose on its order form — $250 a month for semaglutide, $300 for tirzepatide — so titrating up does not raise the bill
The order form shows every price before it asks for your name or any health details
Billed one month at a time with no subscription; a three-month supply paid upfront brings the monthly cost to $200 and about $267

What to weigh up

The homepage advertises weight-loss treatment "from $89/mo" and the weight-loss page "$190/mo", with no term on either and neither matching any price on the order form
The lower price shown first on the order form is a first-month discount; the standing price is the struck-through figure beside it
A three-month supply is billed upfront in one charge, and nothing is refundable once a provider has approved the order and it has shipped

Compounded drugs are not FDA-approved. Understand the medication options.

Check Oak pricing Read the full Oak review

PlexusDx

Shoppers who want one price at every dose, an oral option for either molecule, and all 50 states.

Reasons to consider it

LegitScript Certified, with the seal on the homepage
Same price at every dose, with no membership: semaglutide $189 and tirzepatide $289 month to month, less on 3- and 6-month plans
Both molecules come as weekly injections or daily tablets

What to weigh up

The 'starts at' $149 and $249 figures are 6-month-plan prices; month to month, semaglutide is $189 and tirzepatide $289
The tablets cost more than the shots: oral semaglutide starts at $249/mo and oral tirzepatide at $279/mo on the 6-month plan
No named prescriber, medical director, or specific compounding pharmacy

Compounded drugs are not FDA-approved. Understand the medication options.

Check PlexusDx pricing Read the full PlexusDx review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

OakPlexusDx

Normalized Cost/Month: Oak:
66/100; PlexusDx:
76/100

Price Transparency: Oak:
70/100; PlexusDx:
94/100

Nationwide Access: Oak:
80/100; PlexusDx:
86/100

Formulation Options: Oak:
90/100; PlexusDx:
77/100

Clinical Oversight: Oak:
84/100; PlexusDx:
74/100

Contract Flexibility: Oak:
82/100; PlexusDx:
55/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.