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Head-to-head · Cost-Efficiency Index

Nurx vs VigorMeds

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #411

Nurx

Shoppers who specifically want FDA-approved brand-name Wegovy/Zepbound access through an established telehealth brand and don't want a compounded product.

Visit Nurx
VS
Grade C · #416

VigorMeds

Cost-first shoppers who want a needle-free sublingual GLP-1 that's meaningfully cheaper than the injectable version, from named physicians.

Visit VigorMeds

The verdict

Too close to callGrade C vs C

Nurx and VigorMeds tie on the Cost-Efficiency Index at 50/100, so neither wins outright on the numbers. For most shoppers we'd start with Nurx (ranked #411, a hair above #416) — Shoppers who specifically want FDA-approved brand-name Wegovy/Zepbound access through an established telehealth brand and don't want a compounded product. But VigorMeds is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Nurx.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

45
59

Price Transparency

38
30

Nationwide Access

24
24

Formulation Options

79
77

Clinical Oversight

79
78

Contract Flexibility

55
41

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecNurxVigorMeds
Cost-Efficiency Index50/10050/100
Semaglutide / mo$1,379/mo (brand Wegovy)$199/mo (starting dose, compounded)
Tirzepatide / mo$1,079/mo (brand Zepbound)$299/mo (starting dose, compounded)
Semaglutide / yr (modeled)$16,548$2,388
Tirzepatide / yr (modeled)$12,948$3,588
CoverageCoverage not publishedCoverage not published
Oral / sublingualNoYes
Brand-name accessYesCompounded only
Rank here#411#416

Nurx

50/100

Where the value is

  • Backed by Thirty Madison, an established telehealth parent company that also runs Keeps and Cove
  • Prescribes genuinely FDA-approved brand-name GLP-1s (Wegovy, Zepbound, Ozempic, Mounjaro, Saxenda, Victoza) rather than a compounded substitute
  • Names two Medical Directors on its team page (Dr. Peter Young, Dr. Neil Zlatniski)

The tradeoffs

  • Sells NO compounded semaglutide or tirzepatide at any price — a prior dataset's '$179/mo compounded' figure does not describe any product actually on this site
  • Nurx's own advertised medication prices ($1,000-$1,300/mo) are Nurx's estimate of what the PHARMACY will charge, not a price Nurx guarantees or collects — actual cost varies by pharmacy and insurance
Visit Nurx

Full Nurx review →

VigorMeds

50/100

Where the value is

  • Both injectable and needle-free sublingual forms of semaglutide ($139/mo) and tirzepatide ($159/mo) — the sublingual tier is $60-$140/mo cheaper than the injectable tier
  • Named, credentialed clinicians reviewing cases: Dr. Anthony Kane MD, Dr. Claudia Mondragon MD, Dr. Kevin Kargman MD, Stephanie Kowatch MSN FNP-C
  • 'Pay upon medical approval' — no charge until a provider signs off on treatment, plus a 30-day satisfaction guarantee

The tradeoffs

  • The dedicated 'States We Serve' page names zero actual states in its crawlable content — only vague buckets like 'Coming soon' and 'Room to grow'
  • The FIRST100 promo code discounts whichever tier is chosen by $100 for the first month, so the price shown at signup is not the ongoing rate
Visit VigorMeds

Full VigorMeds review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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