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Head-to-head · Cost-Efficiency Index

NP2GO vs KERNX Health

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #35

NP2GO

Shoppers inside its 40 served states who want both molecules disclosed and will vet the pharmacy themselves.

Visit NP2GO
VS
Grade C · #36

KERNX Health

Shoppers comparing the real cost at their prescribed dose rather than the advertised entry price.

Visit KERNX Health

The verdict

Too close to callGrade C vs C

NP2GO and KERNX Health tie on the Cost-Efficiency Index at 79/100, so neither wins outright on the numbers. For most shoppers we'd start with NP2GO (ranked #35, a hair above #36) — Shoppers inside its 40 served states who want both molecules disclosed and will vet the pharmacy themselves. But KERNX Health is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs NP2GO.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

79
68

Price Transparency

79
88

Nationwide Access

84
92

Formulation Options

77
60

Clinical Oversight

76
80

Contract Flexibility

80
86

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecNP2GOKERNX Health
Cost-Efficiency Index79/10079/100
Semaglutide / mo$150/mo$129/mo (compounded)
Tirzepatide / mo$250/mo$229/mo (compounded)
Semaglutide / yr (modeled)$1,800$1,548
Tirzepatide / yr (modeled)$3,000$2,748
CoverageAK, AZ, AR, CA, CO, CT, DE, DC, FL, HI, ID, IL, IA, KS, KY, ME, MD, MA, MI, MN, MT, NE, NV, NH, NJ, NM, NY, ND, OK, OR, PA, RI, SD, TX, UT, VT, VA, WA, WV, WYAll 50 states
Oral / sublingualNoNo
Brand-name accessCompounded onlyCompounded only
Rank here#35#36

NP2GO

79/100

Where the value is

  • Both molecules disclosed — $150 semaglutide / $250 tirzepatide — for straightforward cost modeling
  • Broad 40-state footprint — wider than most non-nationwide operators
  • Flat, predictable pricing

The tradeoffs

  • 40 states, not all 50 — a coverage gamble that dents its access score
  • Not LegitScript-certified — oversight harder to verify
Visit NP2GO

Full NP2GO review →

KERNX Health

79/100

Where the value is

  • Names individual licensed providers (MDs and NPs) with credentials rather than a vague 'our doctors' claim
  • Serves all 50 states through a licensed physician network
  • Publishes the full dose ladder for both molecules — semaglutide to $199, tirzepatide to $329 — so the cost at a higher dose is knowable before starting

The tradeoffs

  • A separate one-time consultation fee of $25 to $60 applies on top of the first month's medication cost
  • No specific compounding pharmacy partner is named anywhere public
Visit KERNX Health

Full KERNX Health review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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