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Head-to-head · Cost-Efficiency Index

Novi vs Prime Doctor RX

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #105

Novi

Shoppers drawn to the lowest flat headline price in this batch, if they're comfortable that dosing, coverage states, and pharmacy details aren't published anywhere on the site.

Visit Novi
VS
Grade C · #110

Prime Doctor RX

Someone who will convert every figure into four-week cycles before comparing it with anything else here.

Visit Prime Doctor RX

The verdict

Too close to callGrade C vs C

Novi and Prime Doctor RX tie on the Cost-Efficiency Index at 69/100, so neither wins outright on the numbers. For most shoppers we'd start with Novi (ranked #105, a hair above #110) — Shoppers drawn to the lowest flat headline price in this batch, if they're comfortable that dosing, coverage states, and pharmacy details aren't published anywhere on the site. But Prime Doctor RX is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Novi.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

87
70

Price Transparency

94
60

Nationwide Access

24
64

Formulation Options

79
84

Clinical Oversight

87
80

Contract Flexibility

20
62

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecNoviPrime Doctor RX
Cost-Efficiency Index69/10069/100
Semaglutide / mo$99/mo (all doses, promotional rate, compounded)$249 every four weeks — thirteen charges a year, not twelve
Tirzepatide / mo$133/mo (all doses, promotional rate, compounded)$339 every four weeks — thirteen charges a year, not twelve
Semaglutide / yr (modeled)$1,188$2,988
Tirzepatide / yr (modeled)$1,596$4,068
CoverageCoverage not publishedConfirmed at intake, not published
Oral / sublingualNoYes
Brand-name accessYesCompounded only
Rank here#105#110

Novi

69/100

Where the value is

  • Lowest advertised entry price in this entire batch for both drugs ($99 semaglutide / $133 tirzepatide)
  • LegitScript certified, independently verifiable via the linked legitscript.com record
  • States one flat price per dose with no separate visit fee and free shipping

The tradeoffs

  • No published mg dose, supply duration, state-coverage list, named medical director, or named compounding pharmacy anywhere on the site or its help center — the least transparent operational disclosure of any company researched in this batch
  • The advertised $99/$133 rate is displayed against a live countdown timer ('price increases in...') next to a claimed $299 original price, a scarcity tactic that makes it unclear whether this is a genuine standing rate or a recurring promotional one
Visit Novi

Full Novi review →

Prime Doctor RX

69/100

Where the value is

  • The full ladder for all three weight-loss products and for TRT sits on the homepage before any intake
  • Every card's footnote says the starting price is the 52-week prepay, in full
  • The four-week shipping cycle is disclosed in that same footnote rather than left to a bank statement

The tradeoffs

  • Its own arithmetic proves the 28-day cycle — $3,497 divided by thirteen is exactly $269, and nothing on the page divides cleanly by calendar months
  • A year of month-to-month tirzepatide therefore costs $4,407 rather than the $4,068 per-month pricing implies
Visit Prime Doctor RX

Full Prime Doctor RX review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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