Head-to-head · Cost-Efficiency Index
Nova vs One80Rx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Nova
Readers who want the membership inside the quoted price rather than added to it, and who want a daily sublingual option beside the injection.
Visit NovaOne80Rx
Shoppers who want an injectable or oral GLP-1 with peptide therapies on the same account and will confirm their exact price after the provider review.
Visit One80RxThe verdict
Nova and One80Rx tie on the Cost-Efficiency Index at 72/100, so neither wins outright on the numbers, so choose on fit. Nova: Readers who want the membership inside the quoted price rather than added to it, and who want a daily sublingual option beside the injection. One80Rx: Shoppers who want an injectable or oral GLP-1 with peptide therapies on the same account and will confirm their exact price after the provider review.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Nova.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Nova | One80Rx |
|---|---|---|
| Cost-Efficiency Index | 72/100 | 72/100 |
| Semaglutide / mo | $198/moMonth-to-month all-in (medication plus the $99/mo membership; a "Starting at" floor that rises with dose) | $129/moStarting price, compounded; confirmed after provider review |
| Tirzepatide / mo | $210/moMonth-to-month all-in (same bundle; also a "Starting at" floor) | $229/moStarting price, compounded; confirmed after provider review |
| Semaglutide / yr (modeled) | $2,376 | $1,548 |
| Tirzepatide / yr (modeled) | $2,520 | $2,748 |
| Coverage | 49 states | Not published |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #101 | #103 |
Nova
72/100Where the value is
- Quotes one all-in figure that already contains the $99 monthly membership, the medication and refrigerated shipping, so the membership is not a surprise at checkout
- Names a medical director and a nurse practitioner with credentials, training and residency detail
- Prices a daily oral route for both molecules alongside the weekly injections
The tradeoffs
- Its pages show more than one set of prices at once ($198 and $210 in the hero, $229 and $279 in its own FAQ), so confirm the figure at checkout
- The FAQ's own arithmetic does not reach the headline — $99 membership plus $130 medication is $229, not the $198 quoted above it
One80Rx
72/100Where the value is
- Starting prices for every program are listed on its treatments page: semaglutide $129, a GLP-1 microdose $149, an oral GLP-1 $149 and tirzepatide $229 a month
- Promises flat-rate pricing with no consultation charge and no surcharge when your dose changes
- You pay $0 if you aren't approved, and shipping is free in two to three days
The tradeoffs
- Every price is a "from" figure, and the site says plans are confirmed after provider review, so the price for your dose isn't published
- The semaglutide and tirzepatide program pages show no price at all; the figures appear only on the homepage banner and the treatments list
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.