Nex Gen Health Rx vs PlushCare

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Nex Gen Health Rx

Provider comparison

Shoppers who want a named pharmacy and an itemized checkout, and who will read the homepage figure as the annual prepay it is.

Semaglutide / month: $190Per 30-day supply month-to-month (the homepage's $99 is the 360-day prepay rate)
Tirzepatide / month: $239Per 30-day supply month-to-month (the homepage's $149 is the 360-day prepay rate)

Index 62/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Nex Gen Health Rx pricing Read review

PlushCare

Provider comparison

Patients who want a real board-certified physician managing GLP-1s alongside general primary care, and are prepared to navigate insurance or a manufacturer cash-pay program rather than a single flat price.

Semaglutide / month: $499/moBrand Wegovy through NovoCare Pharmacy, plus a separate fee
Tirzepatide / month: $299/mo2.5 mg brand Zepbound vial through LillyDirect; $399 at 5 mg, $449 at 7.5 mg and up, plus a separate fee

Index 61/100 · Grade CChecked October 2026

Check PlushCare pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Nex Gen Health Rx has the higher Cost-Efficiency Index: 62/100 versus 61/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Nex Gen Health Rx: Coverage not published
PlushCare: All 50 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Nex Gen Health Rx

PlushCare

Semaglutide / month: Nex Gen Health Rx: $190Per 30-day supply month-to-month (the homepage's $99 is the 360-day prepay rate); PlushCare: $499/moBrand Wegovy through NovoCare Pharmacy, plus a separate fee

Tirzepatide / month: Nex Gen Health Rx: $239Per 30-day supply month-to-month (the homepage's $149 is the 360-day prepay rate); PlushCare: $299/mo2.5 mg brand Zepbound vial through LillyDirect; $399 at 5 mg, $449 at 7.5 mg and up, plus a separate fee

Semaglutide / year (modeled): Nex Gen Health Rx: $2,280; PlushCare: $6,228Includes $19.99/mo membership

Tirzepatide / year (modeled): Nex Gen Health Rx: $2,868; PlushCare: $3,828Includes $19.99/mo membership

State availability: Nex Gen Health Rx: Coverage not published; PlushCare: All 50 states

Oral / sublingual option listed: Nex Gen Health Rx: Not listed; PlushCare: Not listed

Brand-name access listed: Nex Gen Health Rx: Not confirmed; PlushCare: Yes

Provider facts checked: Nex Gen Health Rx: October 2026; PlushCare: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Nex Gen Health Rx

Shoppers who want a named pharmacy and an itemized checkout, and who will read the homepage figure as the annual prepay it is.

Reasons to consider it

Names its pharmacy, Manifest Pharmacy, with a street address, and states the 503A class on the product pages
The checkout itemizes what the price already covers, showing doctor support and monitoring at $99 and overnight shipping at $40 both marked free
Full 30-, 90-, 180- and 360-day price ladders for both molecules are shown on the product page, and checkout charges the same total

What to weigh up

The homepage prints "for as low as $99.00 a month" and "$149.00 a month" with no basis stated; the basis appears only on a separate landing page, and it is a twelve-month plan paid in full
That landing page sells $99 as "every month", "fixed price" and "price never increases" while its own fine print makes it conditional on $1,188 paid upfront
No legal entity is published anywhere, so an enforcement screen by name cannot reach a letter filed against whatever company operates the site

Compounded drugs are not FDA-approved. Understand the medication options.

Check Nex Gen Health Rx pricing Read the full Nex Gen Health Rx review

PlushCare

Reasons to consider it

Board-certified physicians (not NP-only) available in all 50 states for general virtual primary care
Lists the Zepbound self-pay prices by dose on its own page: vials at $299, $399 and $449 a month, pens at $650
Owned by Transcarent, a venture-backed platform with a named, traceable corporate lineage

What to weigh up

Compounded semaglutide ($149 at 0.25 mg, $299 above) is offered only while the brand drug is on FDA's shortage list, and compounded options only in 40 states plus DC
A $19.99/mo membership (first month free) and, without insurance, a $129 visit come on top of the medication price
The Wegovy page still quotes a $199 first-months price 'valid through March 2026', a date that has passed; its own headline says from $499

Check PlushCare pricing Read the full PlushCare review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Nex Gen Health RxPlushCare

Normalized Cost/Month: Nex Gen Health Rx:
63/100; PlushCare:
27/100

Price Transparency: Nex Gen Health Rx:
92/100; PlushCare:
64/100

Nationwide Access: Nex Gen Health Rx:
24/100; PlushCare:
86/100

Formulation Options: Nex Gen Health Rx:
66/100; PlushCare:
79/100

Clinical Oversight: Nex Gen Health Rx:
60/100; PlushCare:
82/100

Contract Flexibility: Nex Gen Health Rx:
67/100; PlushCare:
41/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.