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Head-to-head · Cost-Efficiency Index

NewSelf vs AgelessRx

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #6

NewSelf

Budget shoppers who want a verified all-50 program and one of the lowest disclosed tirzepatide prices in the value tier.

Visit NewSelf
VS
Grade B · #15

AgelessRx

Budget-first semaglutide shoppers who also want a longevity-medicine framing and occasional brand access.

Visit AgelessRx

The verdict

Winner · NewSelfGrade B+ vs B

NewSelf takes it, leading the Cost-Efficiency Index 87 to 85. $100 semaglutide and $144 tirzepatide, nationwide and LegitScript-verified — near-identical value to the cheapest verified names, with the tirzepatide price a hair lower than most. AgelessRx still earns a BBudget-first semaglutide shoppers who also want a longevity-medicine framing and occasional brand access.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs NewSelf.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

94
84

Price Transparency

87
78

Nationwide Access

96
76

Formulation Options

78
83

Clinical Oversight

86
83

Contract Flexibility

82
85

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecNewSelfAgelessRx
Cost-Efficiency Index87/10085/100
Semaglutide / mo$100/mo$139/mo
Tirzepatide / mo$144/moNot disclosed
Semaglutide / yr (modeled)$1,200$1,668
Tirzepatide / yr (modeled)$1,728
CoverageAll 50 statesNot disclosed
Oral / sublingualNoNo
Brand-name accessCompounded onlyYes
Rank on the board#6#15

NewSelf

87/100

Where the value is

  • $100 semaglutide / $144 tirzepatide — one of the cheapest verified combined prices on the board
  • Nationwide all-50 coverage with both molecules published up front
  • LegitScript-certified pharmacy behind the low price

The tradeoffs

  • Compounded only — no brand-name or oral option
  • Newer consumer brand with a thin public track record
Visit NewSelf

Full NewSelf review →

AgelessRx

85/100

Where the value is

  • Low disclosed semaglutide price at $139/mo
  • Offers some brand-name access
  • Established longevity brand

The tradeoffs

  • Tirzepatide price not disclosed — you can't fully model total cost
  • States-served not disclosed
Visit AgelessRx

Full AgelessRx review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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