Head-to-head · Cost-Efficiency Index
Navio MD vs Clume Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Navio MD
Shoppers who want compounded tirzepatide with a brand-name fallback path on the same platform, 48 states.
Visit Navio MDClume Health
Readers who want the dispensing pharmacies named up front and do not need the price broken out by molecule.
Visit Clume HealthThe verdict
Navio MD and Clume Health tie on the Cost-Efficiency Index at 73/100, so neither wins outright on the numbers. For most shoppers we'd start with Navio MD (ranked #63, a hair above #66) — Shoppers who want compounded tirzepatide with a brand-name fallback path on the same platform, 48 states. But Clume Health is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Navio MD.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Navio MD | Clume Health |
|---|---|---|
| Cost-Efficiency Index | 73/100 | 73/100 |
| Semaglutide / mo | $345/mo (brand Ozempic) | $259/month month-to-month (one Signature price covers semaglutide or tirzepatide, oral or injectable; $186/mo needs a 52-week plan) |
| Tirzepatide / mo | $189/mo (starting dose, compounded) | $259/month month-to-month (the same Signature price; $186/mo needs a 52-week plan) |
| Semaglutide / yr (modeled) | $4,140 | $3,108 |
| Tirzepatide / yr (modeled) | $2,268 | $3,108 |
| Coverage | 48 states | All 50 states |
| Oral / sublingual | No | Yes |
| Brand-name access | Yes | Compounded only |
| Rank here | #63 | #66 |
Navio MD
73/100Where the value is
- LegitScript certified with board-certified providers claimed
- Both compounded and brand-name options on one platform
- 48-state coverage with the two exclusions (AL, MS) explicitly disclosed rather than hidden
The tradeoffs
- No compounded semaglutide offered — only brand-name Ozempic for that molecule, at a much higher price than compounded competitors
- All prices are 'as low as' floors; the exact dose tied to each starting price is not published
Clume Health
73/100Where the value is
- Names all four dispensing pharmacies with street addresses, phone numbers and websites, so a buyer can look up who actually compounds the prescription
- The price is published before the intake and covers the consultation, ongoing oversight, the medication and delivery
- One figure covers semaglutide, tirzepatide, oral and injectable, so switching molecule or route does not change the bill
The tradeoffs
- Both headline prices on the homepage match nothing on sale: "*$199/month" against real floors of $259 and $219, and "*$159/month" against $216 — and neither asterisk resolves to a footnote
- The cheaper monthly figures are commitments rather than rates: $186 a month requires a 52-week plan and $200 a month a 12-week one
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.