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WeighLab

MEDVi vs PlushCare

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

MEDVi

Provider comparison

Shoppers who want compounded semaglutide with no contract and are budgeting on the $299 refill price, not the first-month sale price.

Semaglutide / month
$299/moMonth-to-month refill price; first month $179, compounded
Tirzepatide / month
Not disclosed
Index 62/100 · Grade CChecked October 2026

PlushCare

Provider comparison

Patients who want a real board-certified physician managing GLP-1s alongside general primary care, and are prepared to navigate insurance or a manufacturer cash-pay program rather than a single flat price.

Semaglutide / month
$499/moBrand Wegovy through NovoCare Pharmacy, plus a separate fee
Tirzepatide / month
$299/mo2.5 mg brand Zepbound vial through LillyDirect; $399 at 5 mg, $449 at 7.5 mg and up, plus a separate fee
Index 61/100 · Grade CChecked October 2026

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

MEDVi has the higher Cost-Efficiency Index: 62/100 versus 61/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

MEDVi
Not published
PlushCare
All 50 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

MEDVi

PlushCare

Semaglutide / month
MEDVi: $299/moMonth-to-month refill price; first month $179, compounded
PlushCare: $499/moBrand Wegovy through NovoCare Pharmacy, plus a separate fee
Tirzepatide / month
MEDVi: Not disclosed
PlushCare: $299/mo2.5 mg brand Zepbound vial through LillyDirect; $399 at 5 mg, $449 at 7.5 mg and up, plus a separate fee
Semaglutide / year (modeled)
MEDVi: $3,588
PlushCare: $6,228Includes $19.99/mo membership
Tirzepatide / year (modeled)
MEDVi: —
PlushCare: $3,828Includes $19.99/mo membership
State availability
MEDVi: Not published
PlushCare: All 50 states
Oral / sublingual option listed
MEDVi: Yes
PlushCare: Not listed
Brand-name access listed
MEDVi: Yes
PlushCare: Yes
Provider facts checked
MEDVi: October 2026
PlushCare: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

MEDVi

Shoppers who want compounded semaglutide with no contract and are budgeting on the $299 refill price, not the first-month sale price.

Reasons to consider it

  • The FAQ states both numbers plainly: $179 for the first month and refills locked in at $299, covering the provider review, the medication and shipping
  • No contract; you can cancel at any time by email or through the patient portal chat
  • Names its partner pharmacies (Triad Rx, RedRock Pharmacy and Beaker Pharmacy & Compounding) and the medical groups behind its providers

What to weigh up

  • The $179 headline is a first-month "FALL Sale" price; every refill after that is $299
  • Cancellation must reach support at least 72 hours before your next billing date, and monthly charges are never refunded once the month has started
  • No state list is published; the terms say to contact customer service to find out whether your state is served

Regulatory note: the FDA issued a warning letter to MEDVi, LLC dba MEDVi in February 2026. We still list and link to MEDVi; you should know the letter is on the public record before you decide.

PlushCare

Patients who want a real board-certified physician managing GLP-1s alongside general primary care, and are prepared to navigate insurance or a manufacturer cash-pay program rather than a single flat price.

Reasons to consider it

  • Board-certified physicians (not NP-only) available in all 50 states for general virtual primary care
  • Lists the Zepbound self-pay prices by dose on its own page: vials at $299, $399 and $449 a month, pens at $650
  • Owned by Transcarent, a venture-backed platform with a named, traceable corporate lineage

What to weigh up

  • Compounded semaglutide ($149 at 0.25 mg, $299 above) is offered only while the brand drug is on FDA's shortage list, and compounded options only in 40 states plus DC
  • A $19.99/mo membership (first month free) and, without insurance, a $129 visit come on top of the medication price
  • The Wegovy page still quotes a $199 first-months price 'valid through March 2026', a date that has passed; its own headline says from $499

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

MEDViPlushCare
Normalized Cost/Month
MEDVi:
50/100
PlushCare:
27/100
Price Transparency
MEDVi:
92/100
PlushCare:
64/100
Nationwide Access
MEDVi:
24/100
PlushCare:
86/100
Formulation Options
MEDVi:
77/100
PlushCare:
79/100
Clinical Oversight
MEDVi:
70/100
PlushCare:
82/100
Contract Flexibility
MEDVi:
67/100
PlushCare:
41/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.