Head-to-head · Cost-Efficiency Index
Medsol RX vs YourEra
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Medsol RX
Shoppers who will actually commit to a 12-month prepay and want the lowest possible locked-in monthly rate.
Visit Medsol RXYourEra
Shoppers chasing the lowest sticker price who will verify what's actually billed after the first month.
Visit YourEraThe verdict
Medsol RX takes it, leading the Cost-Efficiency Index 65 to 62. Medsol RX is a compounded-GLP-1 telehealth clinic selling semaglutide and tirzepatide across four commitment tiers — month-to-month, 3-, 6-, and 12-month prepay — with every tier bundling a dedicated care coach and medical oversight. YourEra still earns a C — Shoppers chasing the lowest sticker price who will verify what's actually billed after the first month.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Medsol RX.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Medsol RX | YourEra |
|---|---|---|
| Cost-Efficiency Index | 65/100 | 62/100 |
| Semaglutide / mo | $199/mo (compounded) | $179/mo (all doses, month-to-month, compounded) |
| Tirzepatide / mo | $259/mo (compounded) | $259/mo (all doses, month-to-month, compounded) |
| Semaglutide / yr (modeled) | $2,388 | $2,148 |
| Tirzepatide / yr (modeled) | $3,108 | $3,108 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #165 | #171 |
Medsol RX
65/100Where the value is
- Every commitment tier bundles a dedicated care coach, custom treatment plan, and medical oversight at no extra charge
- Genuine month-to-month option exists with no long-term lock-in, unlike some peers that require prepay
- HSA/FSA eligible with Klarna financing offered
The tradeoffs
- The eye-catching $129/$199 headline prices require a full 12-month prepay ($1,548-$2,388 charged upfront) — the flexible month-to-month rate is $199/$259, notably higher
- No compounding pharmacy is named — only a generic 'certified U.S. pharmacies' claim
YourEra
62/100Where the value is
- A 6-month prepay drops semaglutide to $99/month, among the lowest compounded-GLP-1 headline prices we track
- No membership-fee structure; the site markets "no hidden fees" and "Same price at every dose"
- Prescriptions are "issued only if deemed medically appropriate" after evaluation by licensed US clinicians, stated plainly
The tradeoffs
- The advertised $99/month requires a 6-month prepay — paying month to month costs $149 for the first month and $179/month after, nearly double the headline
- Tirzepatide's advertised $179 is a first-month intro, not a prepay rung: the page's own words are "Month-to-month intro. Then $259/mo." — so the two molecules' headline discounts work in two different ways on one page
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.