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Head-to-head · Cost-Efficiency Index

Maves vs Rylo Health

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #49

Maves

Shoppers drawn to aggressive low intro pricing on semaglutide who will confirm the exact charge before checkout.

Visit Maves
VS
Grade C · #52

Rylo Health

Shoppers who want one flat all-in monthly rate that doesn't rise as the dose increases.

Visit Rylo Health

The verdict

Winner · MavesGrade C vs C

Maves takes it, leading the Cost-Efficiency Index 76 to 75. Maves (operated by parent company Homera Health) is a men's-health/performance-framed telehealth platform offering compounded semaglutide and tirzepatide plus sermorelin. Rylo Health still earns a CShoppers who want one flat all-in monthly rate that doesn't rise as the dose increases.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Maves.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

82
72

Price Transparency

78
94

Nationwide Access

86
86

Formulation Options

66
66

Clinical Oversight

75
75

Contract Flexibility

55
37

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecMavesRylo Health
Cost-Efficiency Index76/10075/100
Semaglutide / mo$89/mo (starting dose, compounded)$149/mo (all doses, promotional rate, compounded)
Tirzepatide / moNot disclosed$249/mo (all doses, compounded)
Semaglutide / yr (modeled)$1,068$1,788
Tirzepatide / yr (modeled)$2,988
CoverageAll 50 statesAll 50 states
Oral / sublingualNoNo
Brand-name accessYesCompounded only
Rank here#49#52

Maves

76/100

Where the value is

  • LegitScript badge displayed on the site
  • Publishes the FDA compounded-medication disclaimer
  • Low advertised semaglutide entry price ($89-99/mo range)

The tradeoffs

  • The homepage shows two different numbers for the same starting semaglutide tier ($89/month vs $99 first month) with no reconciliation — the real ongoing price cannot be confirmed from the public site
  • Tirzepatide is listed as an offering but no price is published anywhere reachable on the site, confirmed by direct search
Visit Maves

Full Maves review →

Rylo Health

75/100

Where the value is

  • Stated flat pricing regardless of dose — 'No surprise charges, no tiered pricing' — a genuine differentiator versus tiered competitors
  • Medication, provider review, and shipping all stated as included in the quoted price with no add-ons found
  • Names its physician group (Lone Star Virtual Health PLLC) and dispensing pharmacy (VialsRX, Houston TX) rather than leaving both anonymous

The tradeoffs

  • The '$100/$160 First 20 rate' shown prominently on the homepage is limited to the first 20 signups only — most shoppers will pay the higher $149/$249 standard rate, and the promo framing can make the real price look lower than it is
  • The advertised 'quarterly $349/$499' option's actual billing mechanics (one-time total vs. recurring monthly-under-commitment) could not be verified — the product pages that would clarify this render via JavaScript and returned no readable pricing text
Visit Rylo Health

Full Rylo Health review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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