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Head-to-head · Cost-Efficiency Index

MANÜ Telehealth vs Medi-Weightloss

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #357

MANÜ Telehealth

Shoppers who don't mind starting an application before seeing real dose-tier pricing or confirming state eligibility.

Visit MANÜ Telehealth
VS
Grade C · #358

Medi-Weightloss

Shoppers near one of Medi-Weightloss's 130+ US clinics who want in-person labs and are comfortable with location-dependent pricing.

Visit Medi-Weightloss

The verdict

Too close to callGrade C vs C

MANÜ Telehealth and Medi-Weightloss tie on the Cost-Efficiency Index at 54/100, so neither wins outright on the numbers. For most shoppers we'd start with MANÜ Telehealth (ranked #357, a hair above #358) — Shoppers who don't mind starting an application before seeing real dose-tier pricing or confirming state eligibility. But Medi-Weightloss is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs MANÜ Telehealth.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

74
71

Price Transparency

30
20

Nationwide Access

24
24

Formulation Options

66
79

Clinical Oversight

85
87

Contract Flexibility

55
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecMANÜ TelehealthMedi-Weightloss
Cost-Efficiency Index54/10054/100
Semaglutide / mo$122/mo (starting dose, compounded)$99/mo (starting dose, first-month rate, plus a separate fee, compounded)
Tirzepatide / mo$152/mo (starting dose, compounded)$199/mo (starting dose, first-month rate, plus a separate fee, compounded)
Semaglutide / yr (modeled)$1,464$1,188
Tirzepatide / yr (modeled)$1,824$2,388
CoverageCoverage not publishedCoverage not published
Oral / sublingualNoNo
Brand-name accessCompounded onlyYes
Rank here#357#358

MANÜ Telehealth

54/100

Where the value is

  • LegitScript verification seal displayed on the site
  • Describes a genuine physician-prescribing process
  • Uses a named 503A U.S. pharmacy category for dispensing

The tradeoffs

  • Per-day pricing framing obscures the true monthly cost, which is never shown directly
  • Inconsistent per-day figures appeared across different page instances ($4/day vs $5/day)
Visit MANÜ Telehealth

Full MANÜ Telehealth review →

Medi-Weightloss

54/100

Where the value is

  • Over 130 in-person clinic locations across the US with on-site labs and body composition analysis at the new-patient visit
  • Publishes real introductory numbers ($99 semaglutide / $199 tirzepatide first month) rather than staying fully opaque
  • Insurance path available for branded Zepbound/Wegovy/Saxenda, with the site claiming most insured patients 'pay between $0 and $50 per visit'

The tradeoffs

  • The $99/$199 headline figures are explicitly FIRST-MONTH-ONLY; the ongoing self-pay rate 'varies by program and location' and is never published anywhere on the site
  • A separate $199 new-patient visit fee is charged before the first month's medication price even applies
Visit Medi-Weightloss

Full Medi-Weightloss review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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