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Head-to-head · Cost-Efficiency Index

Lumora vs Willow

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #422

Lumora

Cost-first shoppers who want physician-led compounded GLP-1 with labs, follow-up, and peptide options.

Visit Lumora
VS
Grade C · #429

Willow

Cost-first shoppers who want an oral-tablet GLP-1 option at the same price as the injectable, with no annual commitment.

Visit Willow

The verdict

Too close to callGrade C vs C

Lumora and Willow tie on the Cost-Efficiency Index at 49/100, so neither wins outright on the numbers. For most shoppers we'd start with Lumora (ranked #422, a hair above #429) — Cost-first shoppers who want physician-led compounded GLP-1 with labs, follow-up, and peptide options. But Willow is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Lumora.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

43
45

Price Transparency

30
54

Nationwide Access

24
24

Formulation Options

77
51

Clinical Oversight

92
79

Contract Flexibility

55
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecLumoraWillow
Cost-Efficiency Index49/10049/100
Semaglutide / mo$199/mo (starting dose, plus a separate fee, compounded)Not disclosed
Tirzepatide / mo$299/mo (starting dose, compounded)Not disclosed
Semaglutide / yr (modeled)$2,388
Tirzepatide / yr (modeled)$3,588
CoverageCoverage not publishedCoverage not published
Oral / sublingualYesYes
Brand-name accessCompounded onlyCompounded only
Rank here#422#429

Lumora

49/100

Where the value is

  • Compounded semaglutide (5 dose tiers) and tirzepatide (6 dose tiers) in injectable and sublingual forms
  • Physician-founded by board-certified Drs. Sean and Shannon Arora (Arora Health & Aesthetics); clinician reviews every assessment
  • LegitScript certified, HIPAA compliant, medications dispensed through licensed U.S. pharmacy partners

The tradeoffs

  • Pricing is fully gated behind the assessment — no public pricing; actual monthly costs unverifiable without completing intake
  • Compounded medications are not FDA-approved; compounding pharmacy partners not publicly named
Visit Lumora

Full Lumora review →

Willow

49/100

Where the value is

  • Oral tablet formulations of both semaglutide and tirzepatide, priced identically to the injectable versions ($299/mo and $399/mo respectively) — a genuine format choice most compounded-drug competitors don't offer
  • Month-to-month billing with no prepay or annual term required to get the advertised rate
  • Named physician team publicly listed, including Chief Medical Officer Dr. Michael Green, MD, plus 11+ other credentialed MDs/DOs

The tradeoffs

  • Only 34 states served — notably narrower than WeightlessRx's 49-state footprint; residents of the other 16 states plus DC are excluded
  • Site states medication cost 'varies by dosage and prescription' but never discloses what a higher maintenance dose actually costs beyond the $299/$399 starting figures
Visit Willow

Full Willow review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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