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Head-to-head · Cost-Efficiency Index

Lumen Meds vs ZYP Medical

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #328

Lumen Meds

Shoppers who want a domain-matched LegitScript certificate and a flat tirzepatide price, not a semaglutide quote.

Visit Lumen Meds
VS
Grade C · #333

ZYP Medical

Cost-first shoppers who want men in IA, NE, SD, MN, KS, CO or AZ wanting a low starter rate with an oral needle-free option.

Visit ZYP Medical

The verdict

Too close to callGrade C vs C

Lumen Meds and ZYP Medical tie on the Cost-Efficiency Index at 56/100, so neither wins outright on the numbers. For most shoppers we'd start with Lumen Meds (ranked #328, a hair above #333) — Shoppers who want a domain-matched LegitScript certificate and a flat tirzepatide price, not a semaglutide quote. But ZYP Medical is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Lumen Meds.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

52
37

Price Transparency

80
64

Nationwide Access

24
42

Formulation Options

53
77

Clinical Oversight

76
78

Contract Flexibility

55
53

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecLumen MedsZYP Medical
Cost-Efficiency Index56/10056/100
Semaglutide / moNot disclosed$150/mo (starting dose, 3 month plan, plus a separate fee, compounded)
Tirzepatide / mo$196/mo (all doses, plus a separate fee, compounded)$233/mo (starting dose, 3 month plan, plus a separate fee, compounded)
Semaglutide / yr (modeled)$1,800
Tirzepatide / yr (modeled)$2,352$2,796
CoverageCoverage not published6 states
Oral / sublingualNoYes
Brand-name accessCompounded onlyCompounded only
Rank here#328#333

Lumen Meds

56/100

Where the value is

  • Named legal entity with a real street address (Lumen Meds LLC, 128 Sunset Blvd #1214, New Castle, DE)
  • LegitScript verification seal specifically matches the lumenmeds.com domain, with a checkable certificate number (47534109) — unlike some peers whose badge verifies a different domain
  • Tirzepatide priced clearly and flatly at $195.82/month, same price at every dose, with no membership fee

The tradeoffs

  • Semaglutide's price is displayed on the site as literally '$0.00/month' with no explanation and no standard ongoing rate published anywhere checked — a real semaglutide price cannot be confirmed
  • States served are not published anywhere on the site
Visit Lumen Meds

Full Lumen Meds review →

ZYP Medical

56/100

Where the value is

  • Offers a genuine needle-free oral tirzepatide (ODT) option, not just injectable
  • Consult fee is disclosed and itemized ($50, or $29.99 for a shorter returning-patient visit)
  • Recently expanded to 7 states (added Minnesota)

The tradeoffs

  • Advertised $150/$233 prices are explicitly labeled 'starter plans (initial 3 months)' — what they become after 3 months is not published anywhere on the site
  • One-time consult fee ($29.99-$50) is charged on top of the medication price and is non-refundable once the visit occurs
Visit ZYP Medical

Full ZYP Medical review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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