Head-to-head · Cost-Efficiency Index
Loop Health vs Medsol RX
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Loop Health
Cost-first shoppers who want peptide and wellness membership with GLP-1s as one offering.
Visit Loop HealthMedsol RX
Shoppers who will actually commit to a 12-month prepay and want the lowest possible locked-in monthly rate.
Visit Medsol RXThe verdict
Loop Health and Medsol RX tie on the Cost-Efficiency Index at 65/100, so neither wins outright on the numbers. For most shoppers we'd start with Loop Health (ranked #164, a hair above #165) — Cost-first shoppers who want peptide and wellness membership with GLP-1s as one offering. But Medsol RX is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Loop Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Loop Health | Medsol RX |
|---|---|---|
| Cost-Efficiency Index | 65/100 | 65/100 |
| Semaglutide / mo | $199/mo (all doses, microdosed, membership required, compounded) | $199/mo (compounded) |
| Tirzepatide / mo | $299/mo (all doses, microdosed, membership required, compounded) | $259/mo (compounded) |
| Semaglutide / yr (modeled) | $2,388 | $2,388 |
| Tirzepatide / yr (modeled) | $3,588 | $3,108 |
| Coverage | All 50 states | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #164 | #165 |
Loop Health
65/100Where the value is
- Multi-product wellness platform — GLP-1 plus peptides, NAD+, coaching, bloodwork
- Low membership entry point ($79/mo)
- Annual plan includes monthly 'research credit' toward compounds
The tradeoffs
- The medication price is on top of a $1,500-a-year membership, annual-plan only, which the terms confirm is separate from compound and medication costs
- Everything sold here is microdosed — the banner over both products reads 'MICRODOSED GLP-1', which is not a labeled therapeutic dose
Medsol RX
65/100Where the value is
- Every commitment tier bundles a dedicated care coach, custom treatment plan, and medical oversight at no extra charge
- Genuine month-to-month option exists with no long-term lock-in, unlike some peers that require prepay
- HSA/FSA eligible with Klarna financing offered
The tradeoffs
- The eye-catching $129/$199 headline prices require a full 12-month prepay ($1,548-$2,388 charged upfront) — the flexible month-to-month rate is $199/$259, notably higher
- No compounding pharmacy is named — only a generic 'certified U.S. pharmacies' claim
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.