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WeighLab

LifeMD vs Clume Health

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

LifeMD

Provider comparison

Insured shoppers chasing a low brand-name GLP-1 copay who understand that the program fee and the medication are billed separately.

Semaglutide / month
$298/moBrand Wegovy
Tirzepatide / month
$448/moBrand Zepbound vial, starting price, program fee included
Index 73/100 · Grade CChecked October 2026

Clume Health

Provider comparison

Readers who want the dispensing pharmacies named up front and do not need the price broken out by molecule.

Semaglutide / month
$259/monthMonth-to-month (one Signature price covers semaglutide or tirzepatide, oral or injectable; $186/mo needs a 52-week plan)
Tirzepatide / month
$259/monthMonth-to-month (the same Signature price; $186/mo needs a 52-week plan)
Index 73/100 · Grade CChecked September 2026

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Both score 73/100 on the Cost-Efficiency Index. There is no score winner; compare the treatment you need, billing terms and state availability.

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

LifeMD

Clume Health

Semaglutide / month
LifeMD: $298/moBrand Wegovy
Clume Health: $259/monthMonth-to-month (one Signature price covers semaglutide or tirzepatide, oral or injectable; $186/mo needs a 52-week plan)
Tirzepatide / month
LifeMD: $448/moBrand Zepbound vial, starting price, program fee included
Clume Health: $259/monthMonth-to-month (the same Signature price; $186/mo needs a 52-week plan)
Semaglutide / year (modeled)
LifeMD: $3,576
Clume Health: $3,108
Tirzepatide / year (modeled)
LifeMD: $5,376
Clume Health: $3,108
State availability
LifeMD: All 50 states
Clume Health: All 50 states
Oral / sublingual option listed
LifeMD: Yes
Clume Health: Yes
Brand-name access listed
LifeMD: Yes
Clume Health: Not confirmed
Provider facts checked
LifeMD: October 2026
Clume Health: September 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

LifeMD

Insured shoppers chasing a low brand-name GLP-1 copay who understand that the program fee and the medication are billed separately.

Reasons to consider it

  • Prescribes FDA-approved brand-name GLP-1s: the Wegovy pill and pen, Foundayo tablets, and Zepbound vials and pens
  • Publishes self-pay starting prices: Wegovy pill $149, Wegovy pen $199 and Zepbound vial $299 a month, before the program fee
  • Insured patients may pay as little as $0 to $25 per fill, and LifeMD's team runs the insurance check for you

What to weigh up

  • The $149 monthly program fee is charged on top of the medication, so the cheapest self-pay option, the Wegovy pill, comes to about $298 a month
  • The $39 first month is a discount on the program fee only, and page banners quoting $75 or $29 don't say which plan they apply to
  • Zepbound vials start at about $448 a month once the program fee is added

Clume Health

Readers who want the dispensing pharmacies named up front and do not need the price broken out by molecule.

Reasons to consider it

  • Names all four dispensing pharmacies with street addresses, phone numbers and websites, so a buyer can look up who actually compounds the prescription
  • The price is published before the intake and covers the consultation, ongoing oversight, the medication and delivery
  • One figure covers semaglutide, tirzepatide, oral and injectable, so switching molecule or route does not change the bill

What to weigh up

  • Both headline prices on the homepage match nothing on sale: "*$199/month" against real floors of $259 and $219, and "*$159/month" against $216 — and neither asterisk resolves to a footnote
  • The cheaper monthly figures are commitments rather than rates: $186 a month requires a 52-week plan and $200 a month a 12-week one
  • One price covers two molecules and two routes, so no drug-specific or form-specific figure is published at all

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

LifeMDClume Health
Normalized Cost/Month
LifeMD:
46/100
Clume Health:
51/100
Price Transparency
LifeMD:
78/100
Clume Health:
92/100
Nationwide Access
LifeMD:
86/100
Clume Health:
86/100
Formulation Options
LifeMD:
95/100
Clume Health:
77/100
Clinical Oversight
LifeMD:
82/100
Clume Health:
68/100
Contract Flexibility
LifeMD:
67/100
Clume Health:
67/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.