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Head-to-head · Cost-Efficiency Index

iThriveMD vs Peptivo

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #194

iThriveMD

People in the CA/AZ service area who want the option of in-person visits alongside telehealth.

Visit iThriveMD
VS
Grade C · #199

Peptivo

Shoppers who value verifiable named pharmacy and medical-leadership credentials, willing to complete an intake quiz to see final pricing.

Visit Peptivo

The verdict

Too close to callGrade C vs C

iThriveMD and Peptivo tie on the Cost-Efficiency Index at 63/100, so neither wins outright on the numbers. For most shoppers we'd start with iThriveMD (ranked #194, a hair above #199) — People in the CA/AZ service area who want the option of in-person visits alongside telehealth. But Peptivo is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs iThriveMD.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

57
66

Price Transparency

94
78

Nationwide Access

24
24

Formulation Options

66
79

Clinical Oversight

90
77

Contract Flexibility

47
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpeciThriveMDPeptivo
Cost-Efficiency Index63/10063/100
Semaglutide / mo$199/mo (all doses, promotional rate, compounded)$169/mo (compounded)
Tirzepatide / mo$399/mo (microdose tier, starting dose, compounded)$249/mo (compounded)
Semaglutide / yr (modeled)$2,388$2,028
Tirzepatide / yr (modeled)$4,788$2,988
CoverageCoverage not publishedCoverage not published
Oral / sublingualNoNo
Brand-name accessCompounded onlyYes
Rank here#194#199

iThriveMD

63/100

Where the value is

  • LegitScript-certified pharmacy claim, not just a generic compliance statement
  • Real physical locations for patients who want in-person care
  • Flat 'same price at all doses' structure for semaglutide simplifies comparison shopping

The tradeoffs

  • $199 headline price is explicitly a teaser that reverts to $299/mo
  • No individually named medical director
Visit iThriveMD

Full iThriveMD review →

Peptivo

63/100

Where the value is

  • Four named, verifiable compounding pharmacy partners across multiple states
  • Named Chief Medical Innovation Officer (MD) and VP of Pharmacy Operations, plus a physician advisory board
  • Ships to all 50 states

The tradeoffs

  • Exact GLP-1 pricing gated behind an intake quiz, not shown as a static table
  • Company's own sibling NAD+ products use a first-month-then-higher pricing structure, raising unconfirmed suspicion the GLP-1 pricing may work the same way
Visit Peptivo

Full Peptivo review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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