Head-to-head · Cost-Efficiency Index
Invigor Medical vs Enhance MD
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Invigor Medical
Value shoppers who want competitive pricing on both molecules plus a wider wellness/hormone program on one account.
Visit Invigor MedicalEnhance MD
Shoppers who want to see every price on the ladder before they commit, value dose-flat billing and routine lab monitoring, and don't need a brand-name or oral route.
Visit Enhance MDThe verdict
Invigor Medical takes it, leading the Cost-Efficiency Index 88 to 75. Solid mid-market cost on both molecules from an established operator — good value if you also want a broader metabolic and hormone catalog. Enhance MD still earns a C — Shoppers who want to see every price on the ladder before they commit, value dose-flat billing and routine lab monitoring, and don't need a brand-name or oral route.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Invigor Medical.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Invigor Medical | Enhance MD |
|---|---|---|
| Cost-Efficiency Index | 88/100 | 75/100 |
| Semaglutide / mo | $225/mo (starting dose) | $212/mo (first month $112) |
| Tirzepatide / mo | $350/mo (starting dose) | $280/mo (first month $180) |
| Semaglutide / yr (modeled) | $2,700 | $2,544 |
| Tirzepatide / yr (modeled) | $4,200 | $3,360 |
| Coverage | All 50 states | Not disclosed |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank on the board | #8 | #36 |
Invigor Medical
88/100Where the value is
- Competitive mid-market 'starting at' pricing on both semaglutide and tirzepatide
- Licensed in all 50 states, with a named Medical Director (Dr. Hamilton) and five named partner compounding pharmacies
- Both molecules published up front for easy cost modeling
The tradeoffs
- Both prices are floors — no dose-tier breakdown is published, so the real cost at a typical maintenance dose is unknown until intake
- The site names five partner pharmacies but never discloses which one fills a given order
Enhance MD
75/100Where the value is
- Fully published, dose-flat tiered pricing — sema $212/mo, tirz $280/mo, microdose $169/mo, sema+tirz combo $322/mo — no quiz or quote wall
- The rate does not climb as your dose is titrated up, unlike per-mg pricing elsewhere on this board
- Routine lab work at the 6-month mark plus ongoing provider messaging is bundled into the price, not sold separately
The tradeoffs
- Compounded only — no FDA-approved brand-name route (no Wegovy, Ozempic, Mounjaro or Zepbound)
- No oral or sublingual GLP-1 option (injection only)
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.