Head-to-head · Cost-Efficiency Index
InstaRX vs MD Total Wellness
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
InstaRX
Shoppers who want one flat price at every dose, so a dose increase never changes the bill.
Visit InstaRXMD Total Wellness
Orange County residents who want a GLP-1 program with in-person visits and monthly follow-ups at a local physician-owned clinic.
Visit MD Total WellnessThe verdict
InstaRX and MD Total Wellness tie on the Cost-Efficiency Index at 67/100, so neither wins outright on the numbers, so choose on fit. InstaRX: Shoppers who want one flat price at every dose, so a dose increase never changes the bill. MD Total Wellness: Orange County residents who want a GLP-1 program with in-person visits and monthly follow-ups at a local physician-owned clinic.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs InstaRX.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | InstaRX | MD Total Wellness |
|---|---|---|
| Cost-Efficiency Index | 67/100 | 67/100 |
| Semaglutide / mo | $179/mo | $299/moCompounded, any dose after a $199 first month |
| Tirzepatide / mo | $259/mo | $399/moCompounded, any dose after a $299 first month |
| Semaglutide / yr (modeled) | $2,148 | $3,588 |
| Tirzepatide / yr (modeled) | $3,108 | $4,788 |
| Coverage | All 50 states | California only |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #173 | #176 |
InstaRX
67/100Where the value is
- Flat 'same price any dose' model for both drugs ($179/mo semaglutide, $259/mo tirzepatide) — no dose-tier guesswork
- Free expedited shipping stated explicitly
- States medications come 'exclusively from U.S. pharmacies'
The tradeoffs
- The homepage's own '$199 to get started' figure is never explained anywhere on the site — unclear if it's a one-time signup charge, the first month's payment, or an additional charge on top of the $179/$259 monthly prices
- No medical director or named prescriber anywhere — only generic 'third-party professional healthcare providers' language
MD Total Wellness
67/100Where the value is
- Prices are published: semaglutide $199 for the first month then $299 at every dose, tirzepatide $299 then $399 at every dose
- Pay-as-you-go monthly pricing with no contract, and the price includes the medication and the care
- Run by a named surgeon, Dr. Oliak, and a physician assistant, with monthly visits to adjust the dose
The tradeoffs
- You need to visit the clinic in Brea, California; telehealth follow-ups are only for established patients
- The lower first-month figures apply to the starting dose only
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.