Head-to-head · Cost-Efficiency Index
Independent Wellness vs RxPros
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Independent Wellness
Shoppers who want included lab testing from a single named FNP-C, PENDING re-verification of price and state count.
Visit Independent WellnessRxPros
Shoppers who want the lowest ongoing per-month compounded rate and don't mind a higher-priced first order.
Visit RxProsThe verdict
Independent Wellness and RxPros tie on the Cost-Efficiency Index at 68/100, so neither wins outright on the numbers. For most shoppers we'd start with Independent Wellness (ranked #117, a hair above #120) — Shoppers who want included lab testing from a single named FNP-C, PENDING re-verification of price and state count. But RxPros is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Independent Wellness.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Independent Wellness | RxPros |
|---|---|---|
| Cost-Efficiency Index | 68/100 | 68/100 |
| Semaglutide / mo | $249/mo (compounded) | $100/mo (all doses, compounded) |
| Tirzepatide / mo | $379/mo (compounded) | $145/mo (all doses, compounded) |
| Semaglutide / yr (modeled) | $2,988 | $1,200 |
| Tirzepatide / yr (modeled) | $4,548 | $1,740 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #117 | #120 |
Independent Wellness
68/100Where the value is
- Named provider (Bonnie Lea Davis, FNP-C) rather than an anonymous clinician pool
- Lab testing (Quest Labs) stated as included at no extra cost, per indexed content
- Oral sublingual option available in addition to injectables
The tradeoffs
- Site returned 403 Forbidden to every direct access attempt today — nothing here was independently confirmed live, only reconstructed from search snippets
- Search-indexed state coverage (~20 states) conflicts with the current dataset's 'All 50 states' claim — this needs resolving before either number is trusted
RxPros
68/100Where the value is
- Flat recurring price of $99.97/mo (sema) and $144.97/mo (tirz) — no per-mg price increase as you titrate up doses
- No membership fee and no mandatory commitment despite an annual-prepay discount option — 'Cancel Subscription Anytime' stated directly
- Ships a 3-month supply per order rather than monthly reshipments
The tradeoffs
- The advertised $99.97/mo (sema) and $144.97/mo (tirz) rates are NOT what a first-time buyer pays — the actual first order is $149 and $249 respectively, 49-72% higher than the headline
- Specific pharmacy partner is not named — a proprietary system routes among unnamed 503A pharmacies and 'cannot guarantee' which one fills any given order
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.