Head-to-head · Cost-Efficiency Index
HealthRX vs Synergy Rx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
HealthRX
Shoppers who want the whole term ladder published before intake and are reading it carefully enough to spot which rung the headline came from.
Visit HealthRXSynergy Rx
People who want a genuine brand-name route and maximum clinician access, and will accept getting a quote by inquiry.
Visit Synergy RxThe verdict
HealthRX takes it, leading the Cost-Efficiency Index 74 to 72. Publishes its entire term ladder as machine-readable data — and advertises the twelve-month rung, so the price on the tin is roughly half the price you pay month to month. Synergy Rx still earns a C — People who want a genuine brand-name route and maximum clinician access, and will accept getting a quote by inquiry.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs HealthRX.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | HealthRX | Synergy Rx |
|---|---|---|
| Cost-Efficiency Index | 74/100 | 72/100 |
| Semaglutide / mo | $190/mo (all doses, compounded) | From $199/mo |
| Tirzepatide / mo | $239/mo (all doses, compounded) | From $349/mo |
| Semaglutide / yr (modeled) | $2,280 | $2,388 |
| Tirzepatide / yr (modeled) | $2,868 | $4,188 |
| Coverage | All 50 states | Not disclosed |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #46 | #53 |
HealthRX
74/100Where the value is
- All 50 states, printed in the site's own header strip rather than left to the intake quiz
- Specific, checkable LegitScript certificate number (50087439) rather than just a generic badge image
- "Same price at every dose" policy avoids dose-based price creep
The tradeoffs
- The advertised $99 and $179 are twelve-month prepay rungs — $1,188 and $2,148 up front. The standing month-to-month rates are $190 and $239, roughly double and a third higher
- A second discount is stacked on the same headline: $99 semaglutide and $149 tirzepatide are also first-month intro rates on the monthly plan, so month two costs more than month one
Synergy Rx
72/100Where the value is
- Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate, not compounded only
- Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
- A $100 welcome credit applied at checkout, and FSA/HSA eligible
The tradeoffs
- Prices are published as bare “Starting at” figures with no billing cycle or term attached, so a full-year cost still cannot be modeled before an inquiry
- At $349/mo tirzepatide sits roughly $100 above the compounded median we track
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.