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Head-to-head · Cost-Efficiency Index

HealthOn vs Tuyo Health

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #297

HealthOn

Cost-first shoppers comparing HealthOn's monthly, quarterly, and 12-month compounded GLP-1 tiers side by side.

Visit HealthOn
VS
Grade C · #298

Tuyo Health

Shoppers who want a low advertised floor price and are willing to confirm the actual dose-tier cost before committing.

Visit Tuyo Health

The verdict

Too close to callGrade C vs C

HealthOn and Tuyo Health tie on the Cost-Efficiency Index at 57/100, so neither wins outright on the numbers. For most shoppers we'd start with HealthOn (ranked #297, a hair above #298) — Cost-first shoppers comparing HealthOn's monthly, quarterly, and 12-month compounded GLP-1 tiers side by side. But Tuyo Health is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs HealthOn.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

49
57

Price Transparency

78
78

Nationwide Access

24
24

Formulation Options

79
79

Clinical Oversight

67
64

Contract Flexibility

47
33

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecHealthOnTuyo Health
Cost-Efficiency Index57/10057/100
Semaglutide / mo$189/mo (1.5 mg dose, compounded)$155/mo (starting dose, compounded)
Tirzepatide / mo$295/mo (10 mg dose, compounded)$279/mo (starting dose, compounded)
Semaglutide / yr (modeled)$2,268$1,860
Tirzepatide / yr (modeled)$3,540$3,348
CoverageCoverage not publishedCoverage not published
Oral / sublingualNoNo
Brand-name accessYesYes
Rank here#297#298

HealthOn

57/100

Where the value is

  • Both compounded semaglutide ($189/mo) and tirzepatide ($295/mo) are priced on their own dedicated product pages, not gated behind an intake
  • Quarterly and 12-month prepay options are disclosed with real dollar savings ($549/quarter and $837/quarter respectively)
  • Independent third-party batch testing for potency, sterility, pH, and endotoxins is disclosed as a stated policy

The tradeoffs

  • The site's sitewide 'Starting at $155/mo*' nav banner is not specific to either medication and requires a 12-month prepay commitment to actually reach — a shopper skimming only the banner will underestimate the real starting cost by $34-140/mo
  • No named prescriber, medical director, or specific compounding pharmacy anywhere on the pages checked
Visit HealthOn

Full HealthOn review →

Regulatory note: the FDA issued a warning letter to Healthon Inc. dba Healthon in September 2025. We still list and link to HealthOn; you should know the letter is on the public record before you decide.

Tuyo Health

57/100

Where the value is

  • Quarterly lab work is explicitly bundled into the compounded-track price, unlike sites that omit lab monitoring entirely
  • Offers both compounded and branded (insurance-eligible) tracks on the same platform
  • LegitScript certified

The tradeoffs

  • Both headline prices are explicit 'as low as' floors with no dose-tier table published — the real cost for a titrated-up dose is unknown from the site
  • No compounding pharmacy or individual prescriber/medical director named anywhere on the page
Visit Tuyo Health

Full Tuyo Health review →

Regulatory note: the FDA issued a warning letter to Tuyo Health, Inc. dba Tuyo Health in September 2025. We still list and link to Tuyo Health; you should know the letter is on the public record before you decide.

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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