Head-to-head · Cost-Efficiency Index
He & She MD vs MyFastRx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
He & She MD
Shoppers comparing injectable semaglutide specifically, where the advertised $199 genuinely is the standing price — not oral semaglutide or tirzepatide, which roll higher after 6 months.
Visit He & She MDMyFastRx
Cost-first shoppers who want cash-pay shoppers comfortable prepaying several months upfront to reach the lowest per-month compounded-GLP-1 rate on the market.
Visit MyFastRxThe verdict
MyFastRx takes it, leading the Cost-Efficiency Index 73 to 71. MyFastRx is a cash-pay compounded-GLP-1 platform with a full published price ladder: a $139/mo semaglutide and $199/mo tirzepatide standing month-to-month rate, a discounted first month with a promo code. He & She MD still earns a C — Shoppers comparing injectable semaglutide specifically, where the advertised $199 genuinely is the standing price — not oral semaglutide or tirzepatide, which roll higher after 6 months.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs MyFastRx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | He & She MD | MyFastRx |
|---|---|---|
| Cost-Efficiency Index | 71/100 | 73/100 |
| Semaglutide / mo | $199/mo (month to month, compounded; every lower rate is a prepaid term) | $139/mo (all doses, promotional rate, compounded) |
| Tirzepatide / mo | $299/mo (month to month, compounded; every lower rate is a prepaid term) | $199/mo (all doses, promotional rate, compounded) |
| Semaglutide / yr (modeled) | $2,388 | $1,668 |
| Tirzepatide / yr (modeled) | $2,388 | $2,388 |
| Coverage | All states except Louisiana (GLP-1) | All 50 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #65 | #68 |
He & She MD
71/100Where the value is
- Compounded semaglutide and tirzepatide (injectable or oral), with brand-name access to Ozempic, Wegovy, and Zepbound also offered
- Named pharmacy (F&F Pharmacies Inc DBA Jungle Jim's Pharmacy, Fairfield OH) and named CMO (Dr. Ozita Cooper, MD)
- Free expedited shipping and unlimited board-certified clinician access
The tradeoffs
- Its own FAQ says the pharmacy it names holds a license in 44 US states, none in California, Nevada, New Jersey, North Carolina, Texas, Massachusetts, Mississippi, New Hampshire, West Virginia or Delaware, and “cannot dispense sterile compounds” — while the same FAQ says GLP-1s ship everywhere except Louisiana. Injectable GLP-1s are sterile compounds, and the site never says which of its two pharmacies covers the gap
- The uniform '$199 to start' banner across all three tracks obscures that only injectable semaglutide holds at $199 ongoing — oral semaglutide rolls to $239/mo and injectable tirzepatide rolls to $289/mo after the first 6-month cycle
MyFastRx
73/100Where the value is
- Publishes a full, specific price ladder (1/3/6/12-month) rather than a single vague 'starting at' figure
- LegitScript certified
- Flat pricing across all doses — no dosage upcharges as you titrate
The tradeoffs
- The true no-commitment monthly rate ($139 sema / $199 tirz) is meaningfully higher than the deep prepay-bundle rates the marketing emphasizes ($79-99 / $124-166) — those low numbers require paying for 3, 6, or 12 months upfront
- The lowest first-month price ($69 / $129) requires entering a promo code and applies to one month only
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.