Head-to-head · Cost-Efficiency Index
Gaya Wellness vs TRT Nation
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Gaya Wellness
Cost-first shoppers who want women 40+ wanting GLP-1 weight loss integrated with menopause/HRT care from an OB/GYN-led practice.
Visit Gaya WellnessTRT Nation
Cost-first shoppers who want men wanting flat-rate compounded tirzepatide alongside a TRT-focused platform.
Visit TRT NationThe verdict
Gaya Wellness and TRT Nation tie on the Cost-Efficiency Index at 51/100, so neither wins outright on the numbers. For most shoppers we'd start with Gaya Wellness (ranked #397, a hair above #403) — Cost-first shoppers who want women 40+ wanting GLP-1 weight loss integrated with menopause/HRT care from an OB/GYN-led practice. But TRT Nation is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Gaya Wellness.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Gaya Wellness | TRT Nation |
|---|---|---|
| Cost-Efficiency Index | 51/100 | 51/100 |
| Semaglutide / mo | $149/mo (quarterly plan, compounded) | Not disclosed |
| Tirzepatide / mo | $349/mo (quarterly plan, compounded) | $219/mo |
| Semaglutide / yr (modeled) | $1,788 | — |
| Tirzepatide / yr (modeled) | $4,188 | $2,628 |
| Coverage | 5 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #397 | #403 |
Gaya Wellness
51/100Where the value is
- Named, credentialed medical founder (board-certified OB/GYN) rather than an anonymous clinical team
- Transparent tiered pricing that discloses both the discounted and full month-to-month rate on the same page
- GLP-1 bundled with hormone/menopause care in one program for women 40+
The tradeoffs
- Licensed in only 5 states (FL, NC, VA, IN, TN), sharply limiting who can actually sign up
- Lowest advertised price requires a quarterly upfront commitment, not simple month-to-month
TRT Nation
51/100Where the value is
- Flat $219/mo tirzepatide regardless of dose escalation
- Tirzepatide compounded with B12 to reduce nausea
- Flat plan includes unlimited virtual provider visits
The tradeoffs
- Weight loss is secondary to core TRT business
- Specific pharmacy partner and 503A status not disclosed
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.