Head-to-head · Cost-Efficiency Index
Fridays vs HumeCare+
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Fridays
Shoppers who want the annual-vs-monthly price difference disclosed upfront rather than discovering it after signup.
Visit FridaysHumeCare+
Cost-first shoppers who want not currently recommendable -- pricing is unverifiable and regulatory signals are internally inconsistent.
Visit HumeCare+The verdict
Fridays takes it, leading the Cost-Efficiency Index 45 to 42. Fridays prices compounded semaglutide from $150/mo and tirzepatide from $240/mo, but both figures require a full annual prepay. HumeCare+ still earns a C — Cost-first shoppers who want not currently recommendable -- pricing is unverifiable and regulatory signals are internally inconsistent.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Fridays.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Fridays | HumeCare+ |
|---|---|---|
| Cost-Efficiency Index | 45/100 | 42/100 |
| Semaglutide / mo | $249/mo (starting dose, compounded) | $199/mo (a floor, not the price: visible only after the medical intake; plus a separate fee at enrollment and every refill, never published; no dose stated, compounded) |
| Tirzepatide / mo | $359/mo (starting dose, compounded) | $299/mo (visible only after the medical intake; plus a separate fee at enrollment and every refill, never published; no dose stated, compounded) |
| Semaglutide / yr (modeled) | $2,988 | — |
| Tirzepatide / yr (modeled) | $4,308 | — |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #464 | #470 |
Fridays
45/100Where the value is
- Explicitly discloses BOTH the annual-prepay rate and the true month-to-month rate on the same pricing page for every compounded product, rather than only advertising the lower prepay figure
- Bundles unlimited provider visits, group coaching, dietitian support, and a fitness app into the price with an explicit 'No membership fees, No sign up fees, No lab fees' statement
- Clinical services are sourced from a named, real network (OpenLoop Healthcare Partners) rather than an anonymous 'licensed providers' claim
The tradeoffs
- The advertised $150/$240 headline figures still require a full 12-month prepay to reach; a shopper who misses the '(annual prepay)' qualifier and compares it to a competitor's true monthly rate would understate Fridays' cost by 40-66%
- No compounding pharmacy is named anywhere on the pages read
HumeCare+
42/100Where the value is
- Genuinely prescribes semaglutide or tirzepatide via a named physician (Dr. Aaron Carter, MD, CMO)
- Includes muscle-preservation supplementation (glycine, B12, B6) as standard
- Proprietary 'Hume Pod' body-composition tracking device is a differentiated feature
The tradeoffs
- No actual price could be found anywhere on the live site -- the pricing template shows an unfilled '$[X]/mo' placeholder
- Regulatory badges shown are UK bodies (GPhC, CQC, MHRA) despite the site's own 'USA's No. 1' claim -- an unexplained inconsistency
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.