Head-to-head · Cost-Efficiency Index
Fresh Day Meds vs Zappy Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Fresh Day Meds
Shoppers comfortable prepaying a 3-month quarterly bundle for the lowest per-month rate.
Visit Fresh Day MedsZappy Health
Shoppers who want both compounded and brand GLP-1 options on one platform and are comfortable weighing a recent FDA misbranding finding.
Visit Zappy HealthThe verdict
Fresh Day Meds takes it, leading the Cost-Efficiency Index 70 to 69. Fresh Day Meds is a multi-category telehealth brand (weight loss, hair, testosterone, sexual wellness, longevity) selling compounded semaglutide and tirzepatide with no membership fee and free shipping. Zappy Health still earns a C — Shoppers who want both compounded and brand GLP-1 options on one platform and are comfortable weighing a recent FDA misbranding finding.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Fresh Day Meds.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Fresh Day Meds | Zappy Health |
|---|---|---|
| Cost-Efficiency Index | 70/100 | 69/100 |
| Semaglutide / mo | $140/mo (compounded) | $159/mo (starting dose, compounded) |
| Tirzepatide / mo | $179/mo (compounded) | $279/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | $1,680 | $1,908 |
| Tirzepatide / yr (modeled) | $2,148 | $3,348 |
| Coverage | All 50 states | 42 states |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Yes |
| Rank here | #87 | #93 |
Fresh Day Meds
70/100Where the value is
- No membership fees and free expedited shipping stated on-site
- LegitScript seal displayed
- Transparent quarterly-renewal totals shown next to the monthly-equivalent price, so the prepay isn't hidden
The tradeoffs
- The 'from $99/mo' headline is a new-patient-only, low-dose, 3-month-prepay price ($299 upfront) — the flat month-to-month rate is $140/mo
- No named compounding pharmacy or medical director/prescriber disclosed
Zappy Health
69/100Where the value is
- Both compounded semaglutide/tirzepatide and brand Wegovy/Zepbound pathways offered on one platform
- No insurance or membership required; cash-pay pricing displayed before intake
- LegitScript badge displayed on the site
The tradeoffs
- Does not name its dispensing pharmacy
- No named medical director or prescriber found
Regulatory note: the FDA issued a warning letter to Kare Solutions, LLC dba Zappy in February 2026. We still list and link to Zappy Health; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.