Head-to-head · Cost-Efficiency Index
Enhance MD vs TeleClinic
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Enhance MD
Shoppers who want flat pricing that doesn't rise with the dose, routine lab monitoring and a semaglutide-plus-tirzepatide combo option, and who don't need a brand-name or oral route.
Visit Enhance MDTeleClinic
Shoppers outside California, New Jersey and South Carolina who want a cheap first month and a rate that's locked as the dose goes up.
Visit TeleClinicThe verdict
TeleClinic takes it, leading the Cost-Efficiency Index 78 to 76. TeleClinic's standard rate is $199 a month for compounded semaglutide and $299 for tirzepatide, locked as your dose rises, after a $79 or $149 first month; Rush Pharmacy fills every order. Enhance MD still earns a C — Shoppers who want flat pricing that doesn't rise with the dose, routine lab monitoring and a semaglutide-plus-tirzepatide combo option, and who don't need a brand-name or oral route.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs TeleClinic.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Enhance MD | TeleClinic |
|---|---|---|
| Cost-Efficiency Index | 76/100 | 78/100 |
| Semaglutide / mo | $212/moFirst month $112 | $199/moCompounded, standard monthly rate, same at every dose; $79 first month |
| Tirzepatide / mo | $280/moFirst month $180 | $299/moCompounded, standard monthly rate, same at every dose; $149 first month |
| Semaglutide / yr (modeled) | $2,544 | $2,388 |
| Tirzepatide / yr (modeled) | $3,360 | $3,588 |
| Coverage | 40 states + DC | 47 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #45 | #51 |
Enhance MD
76/100Where the value is
- Every plan is priced on the homepage before any quiz: semaglutide $212, tirzepatide $280, a semaglutide-plus-tirzepatide combo $322 and microdosed tirzepatide $169
- The monthly price stays the same as your dose goes up
- Lab testing every six months and ongoing provider messaging are built into the price rather than sold separately
The tradeoffs
- Compounded only, with no brand-name Wegovy, Ozempic, Mounjaro or Zepbound
- No oral or sublingual GLP-1, so every option is an injection
TeleClinic
78/100Where the value is
- Names its pharmacy (Rush Pharmacy, a 503A compounder) and its physician network (LocumTele)
- Price-lock: the monthly rate stays the same as your dose increases, for as long as you're a member
- Publishes a full list of the 47 states it serves
The tradeoffs
- The $79 and $149 headline prices cover only the first month; after that it's $199 and $299, or $139 and $219 a month for the first quarter if you pay quarterly
- Not available in California, New Jersey or South Carolina
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.