Head-to-head · Cost-Efficiency Index
EllieMD vs PCOS Sisters
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
EllieMD
Shoppers specifically interested in a microdosing protocol with a named compounding pharmacy, not full-dose treatment.
Visit EllieMDPCOS Sisters
Cost-first shoppers who want women with PCOS who want GLP-1 prescribing folded into a specialty metabolic-care membership.
Visit PCOS SistersThe verdict
EllieMD and PCOS Sisters tie on the Cost-Efficiency Index at 52/100, so neither wins outright on the numbers. For most shoppers we'd start with EllieMD (ranked #387, a hair above #390) — Shoppers specifically interested in a microdosing protocol with a named compounding pharmacy, not full-dose treatment. But PCOS Sisters is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs EllieMD.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | EllieMD | PCOS Sisters |
|---|---|---|
| Cost-Efficiency Index | 52/100 | 52/100 |
| Semaglutide / mo | $229/mo (microdose tier, compounded) | Not disclosed |
| Tirzepatide / mo | $239/mo (microdose tier, compounded) | Not disclosed |
| Semaglutide / yr (modeled) | $2,748 | — |
| Tirzepatide / yr (modeled) | $2,868 | — |
| Coverage | Coverage not published | 12 states |
| Oral / sublingual | No | Yes |
| Brand-name access | Yes | Compounded only |
| Rank here | #387 | #390 |
EllieMD
52/100Where the value is
- Names its compounding pharmacy — Clover, a 503A facility — unlike most competitors in this batch that only say 'a licensed U.S. pharmacy'
- Explicitly states 'No hidden membership, shipping, or consultation fees' for the microdose program
- All 50 states served per the site's own claim
The tradeoffs
- The ONLY GLP-1 pricing published anywhere on the site is for the microdose program — a shopper wanting typical-dose semaglutide or tirzepatide will find no price before completing the intake process
- Microdose pricing requires a 12-week (84-day) minimum commitment; no month-to-month option was found
PCOS Sisters
52/100Where the value is
- Dedicated PCOS specialty model with a metabolic weight-loss program and fitness app bundled into the membership
- Two named pharmacy partners with full addresses published (Strive Pharmacy, Gilbert AZ; Striker Pharmacy, Katy TX)
- LegitScript and BBB verification badges both present on-site
The tradeoffs
- The advertised $150/month does NOT include the GLP-1 medication itself — the site's own FAQ confirms medication is billed separately by the pharmacy, so the real all-in cost is higher and undisclosed
- Only 11 states served (not 12), with no public timeline for expansion beyond 'working to expand our coverage'
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.