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Head-to-head · Cost-Efficiency Index

CoreAge Rx vs Medi-Weightloss

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade A · #1

CoreAge Rx

Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.

Visit CoreAge Rx
VS
Grade C · #358

Medi-Weightloss

Shoppers near one of Medi-Weightloss's 130+ US clinics who want in-person labs and are comfortable with location-dependent pricing.

Visit Medi-Weightloss

The verdict

Winner · CoreAge RxGrade A vs C

CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 54. Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. Medi-Weightloss still earns a CShoppers near one of Medi-Weightloss's 130+ US clinics who want in-person labs and are comfortable with location-dependent pricing.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

93
71

Price Transparency

97
20

Nationwide Access

98
24

Formulation Options

84
79

Clinical Oversight

90
87

Contract Flexibility

95
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecCoreAge RxMedi-Weightloss
Cost-Efficiency Index94/10054/100
Semaglutide / mo$99/mo$99/mo (starting dose, first-month rate, plus a separate fee, compounded)
Tirzepatide / mo$149/mo$199/mo (starting dose, first-month rate, plus a separate fee, compounded)
Semaglutide / yr (modeled)$1,188$1,188
Tirzepatide / yr (modeled)$1,788$2,388
CoverageAll 50 statesCoverage not published
Oral / sublingualNoNo
Brand-name accessCompounded onlyYes
Rank here#1#358

CoreAge Rx

94/100

Where the value is

  • Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
  • Both compounded semaglutide and tirzepatide on one account at published prices
  • Available in all 50 states — no coverage gamble

The tradeoffs

  • Not the rock-bottom sticker price — 30 of the 381 priced semaglutide programs we track list a cheaper figure, though most attach a term or a step-up that CoreAge does not
  • No FDA-approved brand-name option (compounded only)
Visit CoreAge Rx

Full CoreAge Rx review →

Medi-Weightloss

54/100

Where the value is

  • Over 130 in-person clinic locations across the US with on-site labs and body composition analysis at the new-patient visit
  • Publishes real introductory numbers ($99 semaglutide / $199 tirzepatide first month) rather than staying fully opaque
  • Insurance path available for branded Zepbound/Wegovy/Saxenda, with the site claiming most insured patients 'pay between $0 and $50 per visit'

The tradeoffs

  • The $99/$199 headline figures are explicitly FIRST-MONTH-ONLY; the ongoing self-pay rate 'varies by program and location' and is never published anywhere on the site
  • A separate $199 new-patient visit fee is charged before the first month's medication price even applies
Visit Medi-Weightloss

Full Medi-Weightloss review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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