Head-to-head · Cost-Efficiency Index
CoreAge Rx vs Luma Health Co
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
CoreAge Rx
Anyone optimizing for real value — a transparent flat price you can model for a full year, nationwide, without a bait-and-switch.
Visit CoreAge RxLuma Health Co
Cost-first shoppers who want no-subscription compounded GLP-1s, free follow-ups and consult discounts for first responders and teachers.
Visit Luma Health CoThe verdict
CoreAge Rx takes it, leading the Cost-Efficiency Index 94 to 74. Best value on the board: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser. Luma Health Co still earns a C — Cost-first shoppers who want no-subscription compounded GLP-1s, free follow-ups and consult discounts for first responders and teachers.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | CoreAge Rx | Luma Health Co |
|---|---|---|
| Cost-Efficiency Index | 94/100 | 74/100 |
| Semaglutide / mo | $149/mo | $120/mo (plus a separate fee, compounded) |
| Tirzepatide / mo | $349/mo | $180/mo (compounded) |
| Semaglutide / yr (modeled) | $1,788 | $1,440 |
| Tirzepatide / yr (modeled) | $4,188 | $2,160 |
| Coverage | All 50 states | 30 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank on the board | #1 | #63 |
CoreAge Rx
94/100Where the value is
- Flat all-in monthly price — no intro rate that silently triples after month one, so the modeled annual cost is the real cost
- Both compounded semaglutide and tirzepatide on one account at published prices
- Available in all 50 states — no coverage gamble
The tradeoffs
- Not the rock-bottom sticker price — cheaper teaser tiers exist (Direct GLP lists $65, Ondra $93 on semaglutide)
- No FDA-approved brand-name option (compounded only)
Luma Health Co
74/100Where the value is
- Transparent, competitive pricing published up front — compounded semaglutide from $120/mo, tirzepatide from $180/mo, retatrutide from $170/mo
- No subscription, monthly fee or membership — a direct-to-patient model where you pay per medication, and follow-up visits are free
- Free initial consults for first responders, law enforcement, military, nurses and teachers ($0), and $25 for other healthcare workers
The tradeoffs
- Offers compounded retatrutide (labeled "RTT/GLP-3"), an investigational triple agonist not FDA-approved — a higher-risk, less-studied option
- Compounded medications only — no brand-name Wegovy, Zepbound or Ozempic — and compounded GLP-1s aren't FDA-reviewed or approved
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.