Head-to-head · Cost-Efficiency Index
Collective vs System Labs
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Collective
Shoppers who will stay on treatment for a full year, where the annual membership divides down over twelve months rather than landing on one.
Visit CollectiveSystem Labs
People looking for NAD+, sermorelin or a MIC+B12 injection through a clinician; anyone after a GLP-1 prescription needs a different provider.
Visit System LabsThe verdict
Collective takes it, leading the Cost-Efficiency Index 65 to 59. Collective sells compounded semaglutide at $59 and tirzepatide at $69 a month, both genuinely medication prices, on top of a $199 annual membership that is required, auto-renewing and not refundable. System Labs still earns a C — People looking for NAD+, sermorelin or a MIC+B12 injection through a clinician; anyone after a GLP-1 prescription needs a different provider.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Collective.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Collective | System Labs |
|---|---|---|
| Cost-Efficiency Index | 65/100 | 59/100 |
| Semaglutide / mo | $59/moFor the medication, plus a required $199/year membership billed separately | Not disclosed |
| Tirzepatide / mo | $69/moFor the medication, plus the same required $199/year membership | Not disclosed |
| Semaglutide / yr (modeled) | $708 | — |
| Tirzepatide / yr (modeled) | $828 | — |
| Coverage | 44 states (not AL, CA, LA, MA, MS or WA) | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #164 | #326 |
Collective
65/100Where the value is
- Both figures are medication prices rather than a care fee with the drug billed on top, and both appear before any intake
- The membership covers unlimited doctor messaging, check-ins, dose adjustments, nutrition support and express cold shipping, all itemized
- A 21-day free trial precedes the first membership charge, and the trial's auto-conversion is stated plainly
The tradeoffs
- The headline "Get GLP-1s at $59/month" leaves out the mandatory $199 annual membership, which appears only in a card panel, a small disclaimer and the FAQ
- The membership is annual and auto-renewing, and all membership fees are non-refundable with no partial-period refund — so the cheapest medication price here cannot be bought for one month
System Labs
59/100Where the value is
- Prices are listed up front, such as MIC+B12 at $89 a month and NAD+ at $149 a month ($89 for the first month)
- Names its compounding pharmacy, The Pharmacy Hub in Miami, in its FAQ
- Names its medical advisors on the homepage and says it serves all 50 states
The tradeoffs
- It doesn't sell semaglutide, tirzepatide or any other GLP-1 medication
- Refunds aren't offered once services are rendered or a prescription is ordered
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.