Head-to-head · Cost-Efficiency Index
Calibrate Health vs Curve
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Calibrate Health
Cost-first shoppers who want insured shoppers who want a year of coaching wrapped around a branded GLP-1, not the cheapest sticker price.
Visit Calibrate HealthCurve
Cost-first shoppers who want legitScript-certified compounded GLP-1 at flat per-dose pricing.
Visit CurveThe verdict
Calibrate Health and Curve tie on the Cost-Efficiency Index at 63/100, so neither wins outright on the numbers. For most shoppers we'd start with Calibrate Health (ranked #190, a hair above #192) — Cost-first shoppers who want insured shoppers who want a year of coaching wrapped around a branded GLP-1, not the cheapest sticker price. But Curve is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Calibrate Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Calibrate Health | Curve |
|---|---|---|
| Cost-Efficiency Index | 63/100 | 63/100 |
| Semaglutide / mo | Not disclosed | $175/mo (compounded) |
| Tirzepatide / mo | Not disclosed | $225/mo (compounded) |
| Semaglutide / yr (modeled) | — | $2,100 |
| Tirzepatide / yr (modeled) | — | $2,700 |
| Coverage | All 50 states | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #190 | #192 |
Calibrate Health
63/100Where the value is
- Year-long 1:1 video coaching, dietitian support, and a behavior-change curriculum — a materially deeper clinical wrap than transactional telehealth competitors
- Insurance-navigation team works to get medication cost down to '$25/month or less' for members with qualifying commercial coverage
- 10%+ weight-loss money-back guarantee is advertised on the pricing page itself, not buried in fine print
The tradeoffs
- The $199/month headline is the coaching fee alone — medication is billed on top, and full cash-pay brand pricing (for anyone without qualifying insurance) is never disclosed on the pricing page
- 3-month minimum commitment ($597 billed as $199/mo) before the plan becomes cancelable month-to-month
Curve
63/100Where the value is
- Offers both compounded semaglutide and tirzepatide, with every dose priced the same so cost does not rise as you titrate up.
- LegitScript-certified (seal #51079066) and names both its 503A compounding pharmacy, VialsRx, and its provider network, Beluga Health.
- Transparent tiered pricing with a real month-to-month option; consultation, medication, and free expedited shipping included, no membership.
The tradeoffs
- Very new (2026 launch) with a thin track record; the site still shows a Webflow template credit and a leftover Cora reference in its Terms.
- The cheapest headline rates ($99 semaglutide / $135 tirzepatide) require a 12-month prepay; true month-to-month is $175 and $225.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.