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Head-to-head · Cost-Efficiency Index

Blue Sky MD vs Calibrate Health

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #188

Blue Sky MD

Cost-first shoppers who want north Carolina residents who want an established, physician-led, LegitScript-certified in-person clinic.

Visit Blue Sky MD
VS
Grade C · #190

Calibrate Health

Cost-first shoppers who want insured shoppers who want a year of coaching wrapped around a branded GLP-1, not the cheapest sticker price.

Visit Calibrate Health

The verdict

Too close to callGrade C vs C

Blue Sky MD and Calibrate Health tie on the Cost-Efficiency Index at 63/100, so neither wins outright on the numbers. For most shoppers we'd start with Blue Sky MD (ranked #188, a hair above #190) — Cost-first shoppers who want north Carolina residents who want an established, physician-led, LegitScript-certified in-person clinic. But Calibrate Health is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Blue Sky MD.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

57
45

Price Transparency

78
54

Nationwide Access

42
86

Formulation Options

66
53

Clinical Oversight

87
93

Contract Flexibility

55
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecBlue Sky MDCalibrate Health
Cost-Efficiency Index63/10063/100
Semaglutide / mo$160/mo (starting dose, compounded)Not disclosed
Tirzepatide / mo$240/mo (starting dose, compounded)Not disclosed
Semaglutide / yr (modeled)$1,920
Tirzepatide / yr (modeled)$2,880
Coverage1 stateAll 50 states
Oral / sublingualNoNo
Brand-name accessCompounded onlyYes
Rank here#188#190

Blue Sky MD

63/100

Where the value is

  • LegitScript-certified with a named, pictured Medical Director (Dr. David LaMond) and a practice history dating to 2008
  • Weekly pricing ($40 semaglutide / $60 tirzepatide) is well below brand-name cost and comparable to many compounded telehealth competitors
  • 7 physical clinic locations across North Carolina (Charlotte, Asheville, Hendersonville, Greensboro, Clemmons, South Charlotte, Mooresville) for patients who want in-person care

The tradeoffs

  • The published $40/$60 per-week price is explicitly labeled 'in-office' on the GLP-1 page, and that specific page never mentions telehealth at all — whether the rate applies to out-of-state or telehealth-only patients is unconfirmed
  • Geographic footprint is North Carolina only; no state-by-state telehealth coverage list is published
Visit Blue Sky MD

Full Blue Sky MD review →

Calibrate Health

63/100

Where the value is

  • Year-long 1:1 video coaching, dietitian support, and a behavior-change curriculum — a materially deeper clinical wrap than transactional telehealth competitors
  • Insurance-navigation team works to get medication cost down to '$25/month or less' for members with qualifying commercial coverage
  • 10%+ weight-loss money-back guarantee is advertised on the pricing page itself, not buried in fine print

The tradeoffs

  • The $199/month headline is the coaching fee alone — medication is billed on top, and full cash-pay brand pricing (for anyone without qualifying insurance) is never disclosed on the pricing page
  • 3-month minimum commitment ($597 billed as $199/mo) before the plan becomes cancelable month-to-month
Visit Calibrate Health

Full Calibrate Health review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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