Head-to-head · Cost-Efficiency Index
Bloom MD vs Onyx Weight Loss
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Bloom MD
Shoppers who want to see exact dose-by-dose pricing before signing up, for either compounded or branded GLP-1s.
Visit Bloom MDOnyx Weight Loss
Patients located in one of Onyx's 8 served states who want a boutique, NP-led clinic bundling weight loss with hormone and peptide care.
Visit Onyx Weight LossThe verdict
Bloom MD and Onyx Weight Loss tie on the Cost-Efficiency Index at 51/100, so neither wins outright on the numbers. For most shoppers we'd start with Bloom MD (ranked #396, a hair above #402) — Shoppers who want to see exact dose-by-dose pricing before signing up, for either compounded or branded GLP-1s. But Onyx Weight Loss is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Bloom MD.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Bloom MD | Onyx Weight Loss |
|---|---|---|
| Cost-Efficiency Index | 51/100 | 51/100 |
| Semaglutide / mo | $295/mo (starting dose, plus a separate fee, compounded) | Not disclosed |
| Tirzepatide / mo | $295/mo (2.2 mg dose, plus a separate fee, compounded) | Not disclosed |
| Semaglutide / yr (modeled) | $3,540 | — |
| Tirzepatide / yr (modeled) | $3,540 | — |
| Coverage | Coverage not published | 8 states |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #396 | #402 |
Bloom MD
51/100Where the value is
- Rare in this batch: publishes exact dollar pricing for every dose tier, pre-signup
- No hidden membership fee on compounded products -- price shown is the full price
- Offers both compounded AND branded (Wegovy/Zepbound) pathways
The tradeoffs
- No individual medical director named -- only a contracted provider group (MDI Medical Group PC)
- No compounding pharmacy named
Onyx Weight Loss
51/100Where the value is
- Clear, specific 8-state service list published
- Bundles weight loss with hormone replacement and peptide therapy under one clinic
- Small team with named founders and identifiable clinical staff
The tradeoffs
- No pricing published anywhere on the public site
- No physician/MD medical director -- leadership is NP/RN-only
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.