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Head-to-head · Cost-Efficiency Index

Blis MD vs OnlyRx

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #174

Blis MD

Shoppers who want the lowest flat, dose-independent price found in this batch and don't need pharmacy/state transparency upfront.

Visit Blis MD
VS
Grade C · #180

OnlyRx

Shoppers who want a 50-state marketplace with multiple pharmacy options and named prescribers.

Visit OnlyRx

The verdict

Too close to callGrade C vs C

Blis MD and OnlyRx tie on the Cost-Efficiency Index at 64/100, so neither wins outright on the numbers. For most shoppers we'd start with Blis MD (ranked #174, a hair above #180) — Shoppers who want the lowest flat, dose-independent price found in this batch and don't need pharmacy/state transparency upfront. But OnlyRx is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Blis MD.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

76
68

Price Transparency

78
78

Nationwide Access

24
24

Formulation Options

66
90

Clinical Oversight

79
72

Contract Flexibility

55
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecBlis MDOnlyRx
Cost-Efficiency Index64/10064/100
Semaglutide / mo$109/mo (compounded)$179/mo (starting dose, compounded)
Tirzepatide / mo$159/mo (compounded)$249/mo (starting dose, compounded)
Semaglutide / yr (modeled)$1,308$2,148
Tirzepatide / yr (modeled)$1,908$2,988
CoverageCoverage not publishedCoverage not published
Oral / sublingualNoYes
Brand-name accessCompounded onlyYes
Rank here#174#180

Blis MD

64/100

Where the value is

  • Genuinely low flat pricing — $109/mo semaglutide and $159/mo tirzepatide, both below most peers researched here
  • Free initial consultation with a licensed provider
  • Flat pricing regardless of dose tier (no escalation disclosed)

The tradeoffs

  • No compounding pharmacy named anywhere on the site
  • No named medical director or prescriber found
Visit Blis MD

Full Blis MD review →

OnlyRx

64/100

Where the value is

  • Serves all 50 states per its own claim, wider than most compounded-GLP-1 competitors
  • Two named prescribers with published NPI numbers (Dr. Ana Lisa Carr, Dr. Kelly Tenbrink), plus two supporting providers
  • Sources medication from four named, recognizable 503A-style pharmacy partners rather than one undisclosed source

The tradeoffs

  • The $179 headline price is explicitly labeled a 'Summer Promo' on the site's own homepage — no post-promo price is published
  • No dose-tier (mg) breakdown is published for any of the four price points
Visit OnlyRx

Full OnlyRx review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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