Head-to-head · Cost-Efficiency Index
Bionomy Health vs Zappy Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Bionomy Health
Cost-first shoppers who want men wanting physician-led GLP-1 plus TRT and longevity add-ons.
Visit Bionomy HealthZappy Health
Shoppers who want both compounded and brand GLP-1 options on one platform and are comfortable weighing a recent FDA misbranding finding.
Visit Zappy HealthThe verdict
Bionomy Health takes it, leading the Cost-Efficiency Index 70 to 69. Bionomy Health is a physician-led, direct-to-consumer men's telehealth service selling compounded GLP-1 weight-loss medication alongside testosterone, peptides and longevity protocols. Zappy Health still earns a C — Shoppers who want both compounded and brand GLP-1 options on one platform and are comfortable weighing a recent FDA misbranding finding.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Bionomy Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Bionomy Health | Zappy Health |
|---|---|---|
| Cost-Efficiency Index | 70/100 | 69/100 |
| Semaglutide / mo | $189/mo (starting dose, compounded) | $159/mo (starting dose, compounded) |
| Tirzepatide / mo | $249/mo (compounded) | $279/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | $2,268 | $1,908 |
| Tirzepatide / yr (modeled) | $2,988 | $3,348 |
| Coverage | 48 states | 42 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #86 | #93 |
Bionomy Health
70/100Where the value is
- Cancellation is genuinely unconditional: no subscription, no card on file, no auto-renewal, no cancellation fee — you pay per refill
- Prices are published before intake on a dedicated GLP-1 page, and the same figures appear in the site's own llms.txt
- Available in 48 states
The tradeoffs
- The $189 is a starting rate, not a flat one: the page says 'From', the product card says 'Starter', and doses are titrated every four weeks with no published price for the dose you end up on
- The homepage says muscle preservation is 'included' while the GLP-1 page sells a Muscle Preserve Pack at $109/mo as a separate line item
Zappy Health
69/100Where the value is
- Both compounded semaglutide/tirzepatide and brand Wegovy/Zepbound pathways offered on one platform
- No insurance or membership required; cash-pay pricing displayed before intake
- LegitScript badge displayed on the site
The tradeoffs
- Does not name its dispensing pharmacy
- No named medical director or prescriber found
Regulatory note: the FDA issued a warning letter to Kare Solutions, LLC dba Zappy in February 2026. We still list and link to Zappy Health; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.