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Head-to-head · Cost-Efficiency Index

Avono Health vs Lumora

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #419

Avono Health

Shoppers specifically wanting an oral-capsule semaglutide option and willing to prepay a full quarter.

Visit Avono Health
VS
Grade C · #422

Lumora

Cost-first shoppers who want physician-led compounded GLP-1 with labs, follow-up, and peptide options.

Visit Lumora

The verdict

Too close to callGrade C vs C

Avono Health and Lumora tie on the Cost-Efficiency Index at 49/100, so neither wins outright on the numbers. For most shoppers we'd start with Avono Health (ranked #419, a hair above #422) — Shoppers specifically wanting an oral-capsule semaglutide option and willing to prepay a full quarter. But Lumora is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Avono Health.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

21
43

Price Transparency

78
30

Nationwide Access

24
24

Formulation Options

64
77

Clinical Oversight

80
92

Contract Flexibility

47
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecAvono HealthLumora
Cost-Efficiency Index49/10049/100
Semaglutide / mo$699/mo (3-month plan, compounded)$199/mo (starting dose, plus a separate fee, compounded)
Tirzepatide / moNot disclosed$299/mo (starting dose, compounded)
Semaglutide / yr (modeled)$8,388$2,388
Tirzepatide / yr (modeled)$3,588
CoverageCoverage not publishedCoverage not published
Oral / sublingualYesYes
Brand-name accessCompounded onlyCompounded only
Rank here#419#422

Avono Health

49/100

Where the value is

  • Offers a genuinely rare oral-capsule semaglutide format, not just injectable
  • Transparent that pricing is a 3-month bundle rather than hiding the prepay structure
  • US-nationwide clinician network claimed

The tradeoffs

  • 'Saves $X vs. monthly' claims can't be verified since the standalone monthly price is never disclosed
  • No tirzepatide offering at all -- semaglutide only
Visit Avono Health

Full Avono Health review →

Lumora

49/100

Where the value is

  • Compounded semaglutide (5 dose tiers) and tirzepatide (6 dose tiers) in injectable and sublingual forms
  • Physician-founded by board-certified Drs. Sean and Shannon Arora (Arora Health & Aesthetics); clinician reviews every assessment
  • LegitScript certified, HIPAA compliant, medications dispensed through licensed U.S. pharmacy partners

The tradeoffs

  • Pricing is fully gated behind the assessment — no public pricing; actual monthly costs unverifiable without completing intake
  • Compounded medications are not FDA-approved; compounding pharmacy partners not publicly named
Visit Lumora

Full Lumora review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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