Aspire Health vs DrBrainRx

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Aspire Health

Provider comparison

Shoppers in its 30 states who want compounded or brand-name GLP-1s with a full price list up front and a small, named clinical team.

Semaglutide / month: $129Per vial at 0.25–0.5 mg (a 5–10 week supply, compounded with B3; plus the required $49/mo care fee; $159–$189 per vial at 1–2.4 mg; brand Wegovy $199–$399 for a 4-week supply)
Tirzepatide / month: $149 per 4 weeksAt 2.5 mg (compounded with B3; plus the required $49/mo care fee; $249–$299 per vial at 5–15 mg; brand Zepbound $299–$449 for a 4-week supply)

Index 71/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Aspire Health pricing Read review

DrBrainRx

Provider comparison

Shoppers who want one compounded price at every dose, pay per refill, and don't mind a $25 monthly care fee on top of the medication.

Semaglutide / month: $154/moAll doses: $129 medication plus the $25 monthly care fee, compounded
Tirzepatide / month: $274/moAll doses up to 15 mg: $249 medication plus the $25 monthly care fee, compounded

Index 70/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check DrBrainRx pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Aspire Health has the higher Cost-Efficiency Index: 71/100 versus 70/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Aspire Health: 30 states
DrBrainRx: Coverage not published

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Aspire Health

DrBrainRx

Semaglutide / month: Aspire Health: $129Per vial at 0.25–0.5 mg (a 5–10 week supply, compounded with B3; plus the required $49/mo care fee; $159–$189 per vial at 1–2.4 mg; brand Wegovy $199–$399 for a 4-week supply); DrBrainRx: $154/moAll doses: $129 medication plus the $25 monthly care fee, compounded

Tirzepatide / month: Aspire Health: $149 per 4 weeksAt 2.5 mg (compounded with B3; plus the required $49/mo care fee; $249–$299 per vial at 5–15 mg; brand Zepbound $299–$449 for a 4-week supply); DrBrainRx: $274/moAll doses up to 15 mg: $249 medication plus the $25 monthly care fee, compounded

Semaglutide / year (modeled): Aspire Health: $2,136Includes $49/mo care fee; DrBrainRx: $1,848

Tirzepatide / year (modeled): Aspire Health: $2,52513 charges, includes $49/mo care fee; DrBrainRx: $3,288

State availability: Aspire Health: 30 states; DrBrainRx: Coverage not published

Oral / sublingual option listed: Aspire Health: Not listed; DrBrainRx: Not listed

Brand-name access listed: Aspire Health: Yes; DrBrainRx: Yes

Provider facts checked: Aspire Health: October 2026; DrBrainRx: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Aspire Health

Shoppers in its 30 states who want compounded or brand-name GLP-1s with a full price list up front and a small, named clinical team.

Reasons to consider it

Both compounded and brand-name options (Wegovy and Zepbound), each priced dose by dose before you book
Free first consultation, and you pay only if you decide to move forward
Lab orders with interpretation are part of the monthly care; the labs themselves can be billed to insurance

What to weigh up

The $49/mo care fee is billed on top of the medication (its FAQ still says $75/mo for the program, so confirm the fee before you enroll)
The price rises with your dose, and a vial lasts anywhere from four to ten weeks, so the monthly cost depends on your dose
Lab costs aren't included in the care fee

Compounded drugs are not FDA-approved. Understand the medication options.

Check Aspire Health pricing Read the full Aspire Health review

DrBrainRx

Shoppers who want one compounded price at every dose, pay per refill, and don't mind a $25 monthly care fee on top of the medication.

Reasons to consider it

Named, credentialed medical director (Dr. Sara Siavoshi, board-certified neurologist and obesity-medicine specialist), not an anonymous provider pool
One medication price at every dose ($129 semaglutide, $249 tirzepatide up to 15 mg), with no upcharge as you titrate up
Refills are explicitly patient-initiated and never auto-charged — a real anti-dark-pattern commitment

What to weigh up

The $129/$249 medication prices don't include the $25 monthly care fee every compounded patient pays, so the real monthly cost is $154/$274
No compounding pharmacy named beyond a generic 'USP-certified pharmacies in the U.S.' reference
It doesn't list the states it serves, so check yours before you start

Compounded drugs are not FDA-approved. Understand the medication options.

Check DrBrainRx pricing Read the full DrBrainRx review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Aspire HealthDrBrainRx

Normalized Cost/Month: Aspire Health:
66/100; DrBrainRx:
74/100

Price Transparency: Aspire Health:
70/100; DrBrainRx:
94/100

Nationwide Access: Aspire Health:
66/100; DrBrainRx:
24/100

Formulation Options: Aspire Health:
79/100; DrBrainRx:
79/100

Clinical Oversight: Aspire Health:
85/100; DrBrainRx:
87/100

Contract Flexibility: Aspire Health:
67/100; DrBrainRx:
61/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.