Best-value alternatives
Alternatives to SynergenX Health
SynergenX Health scores 46/100 on our Cost-Efficiency Index (ranked #461 of 539). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.
- Our #1 pick01A94/ 100Index
CoreAge Rx
Ranked #1Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.
- Sema
- $99/mo
- Tirz
- $149/mo
- Coverage
- All 50 states
- Brand
- Compounded
- 02C46/ 100Index
Liberty
Ranked #460Liberty Weight Loss is a small, NJ-based GLP-1 telehealth operator offering compounded semaglutide at $247 with no published tirzepatide price.
- Sema
- $247/mo (compounded)
- Tirz
- Not disclosed
- Coverage
- Multi-state
- Brand
- Compounded
- 03C46/ 100Index
Genesis Lifestyle Medicine
Ranked #459Genesis Lifestyle Medicine is a hybrid med-spa/telehealth chain with 16 physical locations across 8 states (TN, TX, NV, UT, IN, CO, FL, GA).
- Sema
- Not disclosed
- Tirz
- Not disclosed
- Coverage
- 8 states
- Brand
- Yes
- 04C46/ 100Index
Florida Weight Loss MD
Ranked #458Florida Weight Loss MD (branded as Florida Surgery & Weight Loss Center) is a statewide Florida telehealth practice led by bariatric surgeon Dr. Sergey Terushkin.
- Sema
- Not disclosed
- Tirz
- Not disclosed
- Coverage
- 1 state
- Brand
- Compounded
- 05C46/ 100Index
Chronos Body Health & Wellness
Ranked #457Chronos BHW is a Louisiana-based medical practice led by Medical Director Dr. Mace Scott, offering compounded semaglutide and tirzepatide in-person in Metairie plus telehealth in Louisiana and Texas.
- Sema
- Not disclosed
- Tirz
- Not disclosed
- Coverage
- 2 states
- Brand
- Yes
- 06C46/ 100Index
Better MedSpa
Ranked #456Better MedSpa is a Chicago-based, statewide-Illinois med spa and telehealth practice under medical director Dr. Brett Brechner, DO, offering semaglutide and tirzepatide with an in-person location in Lincoln Park, Chicago.
- Sema
- $300/mo (compounded)
- Tirz
- $400/mo (compounded)
- Coverage
- 1 state
- Brand
- Compounded
- 07C46/ 100Index
10rx
Ranked #45510rx (take10rx.com) is a GLP-1 and peptide weight-loss telehealth service founded by Dr. Michael Wasef, MD, built around a flat quarterly (3-month) prepay pricing model rather than a monthly subscription.
- Sema
- Not disclosed
- Tirz
- Not disclosed
- Coverage
- Multi-state
- Brand
- Compounded
- 08C46/ 100Index
Roen Rx
Ranked #454RoenRx is a multi-specialty telehealth platform (weight loss, primary care, mental health, ED, hair loss) offering compounded semaglutide from $151/mo and tirzepatide from $216/mo as a medication-only add-on to a separately billed membership.
- Sema
- $151/mo (starting dose, 3-month plan, plus a separate fee, compounded)
- Tirz
- $216/mo (starting dose, plus a separate fee, compounded)
- Coverage
- Multi-state
- Brand
- Yes
Regulatory note: the FDA issued a warning letter to Roen Health, Inc. dba RoenRx in June 2026. We still list and link to Roen Rx; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.