Head-to-head · Cost-Efficiency Index
AgelessRx vs Yucca Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
AgelessRx
Budget-first semaglutide shoppers who also want a longevity-medicine framing and occasional brand access.
Visit AgelessRxYucca Health
Shoppers who want a flat monthly price that won't rise as the dose goes up, with the option to pause instead of cancel.
Visit Yucca HealthThe verdict
AgelessRx takes it, leading the Cost-Efficiency Index 85 to 83. A low published semaglutide price with some brand-name options — but tirzepatide is priced only after the intake, so there is no tirzepatide figure to compare. Yucca Health still earns a B — Shoppers who want a flat monthly price that won't rise as the dose goes up, with the option to pause instead of cancel.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs AgelessRx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | AgelessRx | Yucca Health |
|---|---|---|
| Cost-Efficiency Index | 85/100 | 83/100 |
| Semaglutide / mo | $139/mo | $146/moMonth to month, same price at every dose, compounded |
| Tirzepatide / mo | Not disclosed | $258/moMonth to month, same price at every dose, compounded |
| Semaglutide / yr (modeled) | $1,668 | $1,752 |
| Tirzepatide / yr (modeled) | — | $3,096 |
| Coverage | Not disclosed | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #18 | #23 |
AgelessRx
85/100Where the value is
- Low disclosed semaglutide price at $139/mo
- Offers some brand-name access
- Established longevity brand
The tradeoffs
- Tirzepatide price not disclosed — you can't fully model total cost
- States-served not disclosed
Yucca Health
83/100Where the value is
- Each product page shows all three plans: semaglutide is $146 month to month, $140 a month on three months ($420) and $125 on six ($750); tirzepatide is $258, $248 ($744) and $225 ($1,350)
- The price is locked at every dose for as long as your plan stays active, and pausing keeps the lock
- A written six-month promise refunds everything you paid, including medication, if you follow the plan for six months and haven't lost weight from your logged starting weight
The tradeoffs
- The "$125/mo for life" banner is the six-month plan, billed $750 up front; the no-commitment monthly price is $146
- Once a clinician issues your prescription that order is final and can't be refunded, and you must cancel at least 7 days before a renewal to stop it
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.