Head-to-head · Cost-Efficiency Index
24hrDOC vs Center for Medical Weight Loss (CMWL)
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
24hrDOC
Shoppers comparing the ongoing standing price of compounded GLP-1s, not the first-month promotional rate.
Visit 24hrDOCCenter for Medical Weight Loss (CMWL)
Shoppers wanting a long-established national weight-loss brand with all-in bundled pricing.
Visit Center for Medical Weight Loss (CMWL)The verdict
24hrDOC and Center for Medical Weight Loss (CMWL) tie on the Cost-Efficiency Index at 57/100, so neither wins outright on the numbers. For most shoppers we'd start with 24hrDOC (ranked #296, a hair above #300) — Shoppers comparing the ongoing standing price of compounded GLP-1s, not the first-month promotional rate. But Center for Medical Weight Loss (CMWL) is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs 24hrDOC.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | 24hrDOC | Center for Medical Weight Loss (CMWL) |
|---|---|---|
| Cost-Efficiency Index | 57/100 | 57/100 |
| Semaglutide / mo | $249/mo (microdose tier, 2 mg dose, compounded) | $116/mo (starting dose, compounded) |
| Tirzepatide / mo | $339/mo (microdose tier, starting dose, compounded) | $159/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | $2,988 | $1,392 |
| Tirzepatide / yr (modeled) | $4,068 | $1,908 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #296 | #300 |
24hrDOC
57/100Where the value is
- Full struck-through pricing (promo vs. regular) is published on-site before intake, so the true ongoing cost is verifiable rather than hidden
- Both standard and lower-cost microdose options published for each drug
- Fast intake model: '10-minute assessment' with no office visit required
The tradeoffs
- The widely-advertised $149/$239 price is a ONE-TIME first-month discount ('$100 off'); the standing ongoing price is $249/mo semaglutide and $339/mo tirzepatide — about 40% higher
- No compounding pharmacy or medical director named on the site
Regulatory note: the FDA issued a warning letter to 24HrDoc, Inc. dba 24HrDoc in February 2026. We still list and link to 24hrDOC; you should know the letter is on the public record before you decide.
Center for Medical Weight Loss (CMWL)
57/100Where the value is
- Long-established, recognizable national brand
- All-in pricing with no separate membership fee
- Ships to all 50 states
The tradeoffs
- No individual medical director or compounding pharmacy named
- Confusing plan structure -- the '3-month plan' is priced higher per month than the base plan, opposite of typical prepay discounts
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.