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WeighLab

Head-to-head · Cost-Efficiency Index

1st Optimal vs Eviora MD

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Higher scoreGrade C

1st Optimal

Patients who want a named founding physician and a broader functional-medicine/hormone workup alongside GLP-1s.

Visit 1st Optimal
VS
Grade C

Eviora MD

People who want a provider-led compounded GLP-1 plan with regular check-ins and are willing to get a quote before committing.

Visit Eviora MD

The verdict

Too close to callGrade C vs C

1st Optimal and Eviora MD tie on the Cost-Efficiency Index at 41/100, so neither wins outright on the numbers, so choose on fit. 1st Optimal: Patients who want a named founding physician and a broader functional-medicine/hormone workup alongside GLP-1s. Eviora MD: People who want a provider-led compounded GLP-1 plan with regular check-ins and are willing to get a quote before committing.

Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs 1st Optimal.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

45
45

Price Transparency

20
20

Nationwide Access

24
24

Formulation Options

51
40

Clinical Oversight

84
74

Contract Flexibility

37
61

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

Spec1st OptimalEviora MD
Cost-Efficiency Index41/10041/100
Semaglutide / moNot disclosedNot disclosed
Tirzepatide / moNot disclosedNot disclosed
Semaglutide / yr (modeled)——
Tirzepatide / yr (modeled)——
CoverageCoverage not publishedNot published
Oral / sublingualYesNo
Brand-name accessCompounded onlyCompounded only
Rank here#589#595

1st Optimal

41/100

Where the value is

  • Named founder and clinical lead: Dr. Amber Miller, a functional medicine physician
  • LegitScript verification badge displayed
  • No credit card required to start the intake quiz

The tradeoffs

  • No GLP-1 pricing published on its site
  • No compounding pharmacy partner named
Visit 1st Optimal

Full 1st Optimal review →

Eviora MD

41/100

Where the value is

  • Says programs are flat-rate, with no consultation charge and no surcharge when your dose changes
  • $0 if a provider doesn't approve you
  • Includes dose titration, structured check-ins and secure messaging with the care team

The tradeoffs

  • No program shows a price; the only figure is a "from $149/mo" new-patient offer that isn't tied to a specific medication
  • The pharmacy and the medical group are not named
Visit Eviora MD

Full Eviora MD review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

Keep comparing

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