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Head-to-head · Cost-Efficiency Index

1st Optimal vs Cabana

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #518

1st Optimal

Patients who want a named founding physician and a broader functional-medicine/hormone workup alongside GLP-1s.

Visit 1st Optimal
VS
Grade C · #525

Cabana

Shoppers who want a lifestyle-branded concierge wellness experience bundling GLP-1 with other treatments.

Visit Cabana

The verdict

Winner · 1st OptimalGrade C vs C

1st Optimal takes it, leading the Cost-Efficiency Index 41 to 40. 1st Optimal is a Michigan-based hormone and metabolic telehealth practice founded by Dr. Amber Miller, a functional medicine physician, offering GLP-1 weight-loss care alongside broader hormone and lab-based programs. Cabana still earns a CShoppers who want a lifestyle-branded concierge wellness experience bundling GLP-1 with other treatments.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs 1st Optimal.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

45
45

Price Transparency

20
20

Nationwide Access

24
24

Formulation Options

51
64

Clinical Oversight

84
76

Contract Flexibility

37
20

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

Spec1st OptimalCabana
Cost-Efficiency Index41/10040/100
Semaglutide / moNot disclosedNot disclosed
Tirzepatide / moNot disclosedNot disclosed
Semaglutide / yr (modeled)
Tirzepatide / yr (modeled)
CoverageCoverage not publishedCoverage not published
Oral / sublingualYesYes
Brand-name accessCompounded onlyYes
Rank here#518#525

1st Optimal

41/100

Where the value is

  • Named founder and clinical lead: Dr. Amber Miller, a functional medicine physician
  • LegitScript verification badge displayed
  • No credit card required to start the intake quiz

The tradeoffs

  • No GLP-1 pricing published anywhere on the public site
  • No compounding pharmacy partner named
Visit 1st Optimal

Full 1st Optimal review →

Cabana

40/100

Where the value is

  • Offers a semaglutide tablet option in addition to injectables
  • Single, findable headline price ($249/mo starting) visible without an account
  • Explicit disclaimer distinguishing FDA-approved vs. compounded (non-FDA-approved) medications

The tradeoffs

  • Pricing is not broken out by specific drug or dose -- unclear what a semaglutide vs. tirzepatide patient actually pays
  • 'Starting At' framing with no clarification of whether $249 is promotional or standard
Visit Cabana

Full Cabana review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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