Head-to-head · Cost-Efficiency Index
10rx vs SynergenX Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
10rx
Shoppers comfortable prepaying a full 3-month block once pricing is revealed in the quiz flow.
Visit 10rxSynergenX Health
Cost-first shoppers who want men and women already seeking in-person TRT/HRT care who might add GLP-1s as a secondary service -- not a fit for GLP-1-first shoppers.
Visit SynergenX HealthThe verdict
10rx and SynergenX Health tie on the Cost-Efficiency Index at 46/100, so neither wins outright on the numbers. For most shoppers we'd start with 10rx (ranked #455, a hair above #461) — Shoppers comfortable prepaying a full 3-month block once pricing is revealed in the quiz flow. But SynergenX Health is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs 10rx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | 10rx | SynergenX Health |
|---|---|---|
| Cost-Efficiency Index | 46/100 | 46/100 |
| Semaglutide / mo | Not disclosed | Not disclosed |
| Tirzepatide / mo | Not disclosed | Not disclosed |
| Semaglutide / yr (modeled) | — | — |
| Tirzepatide / yr (modeled) | — | — |
| Coverage | Coverage not published | 10 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #455 | #461 |
10rx
46/100Where the value is
- Named founder physician (Dr. Michael Wasef, MD) with a public provider roster
- Flat price promise -- 'your price stays the same across available strengths' even if dose changes
- Free shipping advertised
The tradeoffs
- No dollar pricing published anywhere on the public site -- fully gated behind the quiz/checkout
- Quarterly-only billing structure (3 months upfront) makes month-to-month cost comparison impossible without completing intake
SynergenX Health
46/100Where the value is
- Large in-person clinic footprint (64 locations, 10 states) for patients who prefer face-to-face visits
- Established, multi-service hormone-therapy brand
- One transparent price point exists for hormone lab testing ($99 self-pay)
The tradeoffs
- No GLP-1/semaglutide/tirzepatide pricing published anywhere on the site
- Primarily a TRT/HRT business; weight loss and GLP-1s are an undifferentiated add-on, not a core offering
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.