Head-to-head · Cost-Efficiency Index
Zenbody vs Vital Step
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Zenbody
Shoppers who want the choice of a weekly injection or a daily oral tablet for either semaglutide or tirzepatide, and who will confirm the month-two price before paying.
Visit ZenbodyVital Step
Shoppers who want a GLP-1 tablet option in any state and are willing to finish the intake to see the real monthly price before paying.
Visit Vital StepThe verdict
Zenbody and Vital Step tie on the Cost-Efficiency Index at 65/100, so neither wins outright on the numbers, so choose on fit. Zenbody: Shoppers who want the choice of a weekly injection or a daily oral tablet for either semaglutide or tirzepatide, and who will confirm the month-two price before paying. Vital Step: Shoppers who want a GLP-1 tablet option in any state and are willing to finish the intake to see the real monthly price before paying.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Zenbody.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Zenbody | Vital Step |
|---|---|---|
| Cost-Efficiency Index | 65/100 | 65/100 |
| Semaglutide / mo | $149/moStarting-dose intro price for the injection, compounded; oral tablet from $199 | $161/moLowest advertised rate, compounded; the plan behind it and the regular monthly price appear only after the intake |
| Tirzepatide / mo | $179/moStarting-dose intro price for the injection, compounded; oral tablet from $299 | $198/moLowest advertised rate, compounded; the regular monthly price appears only after the intake |
| Semaglutide / yr (modeled) | $1,788 | $1,932 |
| Tirzepatide / yr (modeled) | $2,148 | $2,376 |
| Coverage | Not published | All 50 states |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #210 | #212 |
Zenbody
65/100Where the value is
- Both semaglutide and tirzepatide come as a weekly injection or a daily oral tablet, with each format priced on its product page
- The monthly price includes the medication, clinical oversight, dose adjustments, care-team messaging and shipping, with no insurance needed
- You can pause or cancel at any time, and a cancellation keeps your access through the end of the billing period
The tradeoffs
- The advertised prices are introductory starting-dose figures; the site says flat monthly pricing applies after the first month but doesn't print that price, so check it at checkout
- The homepage also advertises 40% off your first month without saying which figure the discount applies to
Vital Step
65/100Where the value is
- Semaglutide and tirzepatide both come as weekly injections or daily dissolving tablets
- Publishes a list of all 50 states it ships to
- Free expedited delivery and round-the-clock support, with side-effect questions and dose adjustments included
The tradeoffs
- Only "as low as" figures are published; the plan length behind $161 and $198 and the regular month-to-month price are shown only after the intake
- No refunds at all: the refund policy says all fees and charges are non-refundable, in whole or in part
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.