Head-to-head · Cost-Efficiency Index
Youth & Soul vs MangoRx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Youth & Soul
Shoppers who want a named compounding pharmacy and nationwide shipping with both compounded and branded GLP-1 options in one place.
Visit Youth & SoulMangoRx
Men who want a needle-free semaglutide tablet at one published monthly price.
Visit MangoRxThe verdict
Youth & Soul and MangoRx tie on the Cost-Efficiency Index at 61/100, so neither wins outright on the numbers, so choose on fit. Youth & Soul: Shoppers who want a named compounding pharmacy and nationwide shipping with both compounded and branded GLP-1 options in one place. MangoRx: Men who want a needle-free semaglutide tablet at one published monthly price.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Youth & Soul.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Youth & Soul | MangoRx |
|---|---|---|
| Cost-Efficiency Index | 61/100 | 61/100 |
| Semaglutide / mo | $149/moCompounded | $299/moOral dissolving tablet, 30-day supply, compounded |
| Tirzepatide / mo | $149/moCompounded | Not offered |
| Semaglutide / yr (modeled) | $1,788 | $3,588 |
| Tirzepatide / yr (modeled) | $1,788 | — |
| Coverage | Coverage not published | Not published |
| Oral / sublingual | No | Yes |
| Brand-name access | Yes | Compounded only |
| Rank here | #286 | #289 |
Youth & Soul
61/100Where the value is
- Named, verifiable compounding pharmacy partner (Procompounding Pharmacy) plus a named fulfillment partner (The Pharmacy Hub)
- Claims all-50-state shipping
- LegitScript seal displayed
The tradeoffs
- Its main web address forwards to a differently spelled site, so make sure you're on the right one before entering details
- 'From $149/mo' headline price isn't broken out by exact dose, and the referenced 'Level 1-3' tier structure isn't fully published
MangoRx
61/100Where the value is
- Slim is priced openly on its product page at $299 for a month's supply, with the price locked in and no hidden fees
- A needle-free option: a mint-flavored tablet that dissolves in the mouth, with vitamin B6 added for nausea
- Free provider visits and free shipping on all orders
The tradeoffs
- Only semaglutide in one oral form; no tirzepatide, no injection and no brand-name option
- An oral compounded tablet is a different product from the injections most GLP-1 programs sell, and the site doesn't explain how its doses compare
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.