Head-to-head · Cost-Efficiency Index
YourEra vs Blis MD
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
YourEra
Shoppers chasing the lowest sticker price who will verify what's actually billed after the first month.
Visit YourEraBlis MD
Shoppers who want the lowest flat, dose-independent price found in this batch and don't need pharmacy/state transparency upfront.
Visit Blis MDThe verdict
Blis MD takes it, leading the Cost-Efficiency Index 64 to 62. Blis MD is a telehealth service offering compounded semaglutide ($109/mo) and tirzepatide ($159/mo) at flat monthly rates with a free initial consultation and ongoing provider check-ins. YourEra still earns a C — Shoppers chasing the lowest sticker price who will verify what's actually billed after the first month.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Blis MD.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | YourEra | Blis MD |
|---|---|---|
| Cost-Efficiency Index | 62/100 | 64/100 |
| Semaglutide / mo | $179/mo (all doses, month-to-month, compounded) | $109/mo (compounded) |
| Tirzepatide / mo | $259/mo (all doses, month-to-month, compounded) | $159/mo (compounded) |
| Semaglutide / yr (modeled) | $2,148 | $1,308 |
| Tirzepatide / yr (modeled) | $3,108 | $1,908 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #171 | #174 |
YourEra
62/100Where the value is
- A 6-month prepay drops semaglutide to $99/month, among the lowest compounded-GLP-1 headline prices we track
- No membership-fee structure; the site markets "no hidden fees" and "Same price at every dose"
- Prescriptions are "issued only if deemed medically appropriate" after evaluation by licensed US clinicians, stated plainly
The tradeoffs
- The advertised $99/month requires a 6-month prepay — paying month to month costs $149 for the first month and $179/month after, nearly double the headline
- Tirzepatide's advertised $179 is a first-month intro, not a prepay rung: the page's own words are "Month-to-month intro. Then $259/mo." — so the two molecules' headline discounts work in two different ways on one page
Blis MD
64/100Where the value is
- Genuinely low flat pricing — $109/mo semaglutide and $159/mo tirzepatide, both below most peers researched here
- Free initial consultation with a licensed provider
- Flat pricing regardless of dose tier (no escalation disclosed)
The tradeoffs
- No compounding pharmacy named anywhere on the site
- No named medical director or prescriber found
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.