Head-to-head · Cost-Efficiency Index
Wholesome Clinic vs MadeMed
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Wholesome Clinic
Patients in TX/CO/NM/OK/LA/AR/OR who want GLP-1 weight loss bundled with psychiatric/whole-person care from one provider, and who value transparent dose-tiered pricing.
Visit Wholesome ClinicMadeMed
Shoppers comfortable paying three months at a time who want one flat price at every dose, or a no-needle sublingual semaglutide tablet.
Visit MadeMedThe verdict
Wholesome Clinic and MadeMed tie on the Cost-Efficiency Index at 68/100, so neither wins outright on the numbers, so choose on fit. Wholesome Clinic: Patients in TX/CO/NM/OK/LA/AR/OR who want GLP-1 weight loss bundled with psychiatric/whole-person care from one provider, and who value transparent dose-tiered pricing. MadeMed: Shoppers comfortable paying three months at a time who want one flat price at every dose, or a no-needle sublingual semaglutide tablet.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Wholesome Clinic.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Wholesome Clinic | MadeMed |
|---|---|---|
| Cost-Efficiency Index | 68/100 | 68/100 |
| Semaglutide / mo | $149/mo0.5 mg dose, compounded | $239/moQuarterly plan, billed $717 every 3 months, same price at every dose, compounded |
| Tirzepatide / mo | $349/mo5.0 mg dose, compounded | $399/moQuarterly plan, billed $1,197 every 3 months, same price at every dose, compounded |
| Semaglutide / yr (modeled) | $1,788 | $2,868 |
| Tirzepatide / yr (modeled) | $4,188 | $4,788 |
| Coverage | 7 states | 23 states |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #154 | #161 |
Wholesome Clinic
68/100Where the value is
- Real, named, dual-certified prescriber (Stephanie Ukoha, DNP, FNP-BC, PMHNP-BC)
- Transparent dose-tiered pricing for both injectable and oral GLP-1 options, with no evident promo bait-and-switch
- Oral ODT alternatives offer a notably cheaper entry point ($109/mo semaglutide, $249/mo tirzepatide)
The tradeoffs
- Weight loss is a secondary service line to the clinic's core psychiatry focus, not its specialty
- Only licensed in seven states -- far narrower than most national GLP-1 telehealth competitors
MadeMed
68/100Where the value is
- One flat price at every dose, printed dose by dose on each product page
- Offers sublingual semaglutide tablets ($219 a month quarterly) and oral tirzepatide alongside the injections
- You can cancel or pause in one click from your dashboard, and it emails you 7 days before every charge
The tradeoffs
- There is no monthly plan; the shortest commitment is three months, billed up front
- Injectable semaglutide is offered in only 23 states, fewer than the 40 the service lists overall, so check your state on the product page
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.